UniProt Accession

 HA2B_RAT; P20037 

Genbank Protein ID

 M22366; M31014 

Genbank Nucleotide ID

 AAA42083.1; AAA42083.1 

Protein Name

 Rano class II histocompatibility antigen, B alpha chain 

Protein Synonyms/Alias

 RT1 class II antigen, Ba chain 

Gene Name

 RT1-Ba 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
102	HNLEILMKRSNSTPA	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

 DOMAIN 108 206 Ig-like C1-type.
 REGION 24 111 Alpha-1.
 REGION 112 205 Alpha-2.
 REGION 206 218 Connecting peptide.
 CARBOHYD 145 145 N-linked (GlcNAc...) (Potential).
 DISULFID 134 190 By similarity.  

Keyword

 Complete proteome; Disulfide bond; Glycoprotein; Immunity; Membrane; MHC II; Reference proteome; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 256 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
 GO:0046982; F:protein heterodimerization activity; IDA:RGD.
 GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
 GO:0071385; P:cellular response to glucocorticoid stimulus; IEP:RGD.
 GO:0006955; P:immune response; IEA:InterPro.
 GO:0042130; P:negative regulation of T cell proliferation; IDA:RGD. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR014745; MHC_II_a/b_N.
 IPR001003; MHC_II_a_N. 

Pfam

 PF07654; C1-set
 PF00993; MHC_II_alpha 

SMART

 SM00407; IGc1
 SM00920; MHC_II_alpha 

PROSITE

 PS50835; IG_LIKE
 PS00290; IG_MHC 

PRINTS