UniProt Accession

 IL32_HUMAN; P24001; A6NNM0; A8MPX0; B4DJM1; D3DUB0; D3DUB2; Q5VFH7; Q5VFH8; Q8WV38; Q96GK9 

Genbank Protein ID

 M59807; AY495331; AY495332; AY495333; AY495334; AY495334; AY495334; AK296143; BM825040; AC108134; CH471112; CH471112; CH471112; CH471112; CH471112; CH471112; BC009401; BC018782; BC105602 

Genbank Nucleotide ID

 AAA36367.2; AAS80143.1; AAS80144.1; AAS80145.1; AAS80146.1; AAS80147.1; AAS80148.1; BAG58883.1; EAW85405.1; EAW85406.1; EAW85407.1; EAW85408.1; EAW85409.1; EAW85410.1; AAH09401.1; AAH18782.1; AAI05603.1 

Protein Name

 Interleukin-32 

Protein Synonyms/Alias

 IL-32; Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor 

Gene Name

 IL32 

Gene Synonyms/Alias

 NK4; TAIF 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
28	AIERFYDKMQNAESG	ubiquitination	[1, 2]
75	ELTPLLEKERDGLRC	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF- alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. 

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Cytokine; Reference proteome; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 234 AA 

Protein Sequence

Gene Ontology

 GO:0005615; C:extracellular space; TAS:ProtInc.
 GO:0007155; P:cell adhesion; TAS:ProtInc.
 GO:0006952; P:defense response; TAS:ProtInc.
 GO:0006955; P:immune response; TAS:ProtInc. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS