| Tag | Content |
|---|
| CPLM ID | CPLM-004436 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Anion exchange protein 3 |
Protein Synonyms/Alias | AE 3; Anion exchanger 3; Neuronal band 3-like protein; Solute carrier family 4 member 3 |
Gene Name | Slc4a3 |
Gene Synonyms/Alias | Ae3 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 642 | RREREQTKVEMTTRG | ubiquitination | [1] | | 656 | GGYAAPGKELSLEMG | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Plasma membrane anion exchange protein. |
Sequence Annotation | REGION 708 1227 Membrane (anion exchange).
MOD_RES 170 170 Phosphoserine.
MOD_RES 198 198 Phosphoserine.
MOD_RES 296 296 Phosphoserine.
LIPID 1160 1160 S-palmitoyl cysteine (By similarity).
CARBOHYD 868 868 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Anion exchange; Antiport; Complete proteome; Glycoprotein; Ion transport; Lipoprotein; Membrane; Palmitate; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1227 AA |
Protein Sequence | MANGVIPPPG GASPLPQVRV PLEEPPLGPD VEEEDDDLGK TLAVSRFGDL ISKTPAWDPE 60
KPSRSYSERD FEFHRHTSHH THHPLSARLP PPHKLRRPPP TSARHTRRKR KKEKTSAPPS 120
EGTPPIQEEG GAGAEEEEEE EEEEEGESEA EPVEPLPPGP PQKAKFSIGS DEDDSPGLPV 180
KAPCAKALPS VGLQSDQSPQ RSGSSPSPRA RASRISTEKS RPWSPSASYD LRERLCPGSA 240
LGNPGPEQRV PTDEAEAQML GSADLDDMKS HRLEDNPGVR RHLVKKPSRI QGGRGSPSGL 300
APILRRKKKK KKLDRRPHEV FVELNELMLD RSQEPHWRET ARWIKFEEDV EEETERWGKP 360
HVASLSFRSL LELRRTIAQG AALLDLEQTT LPGIAHLVVE TMIVSDQIRP EDRASVLRTL 420
LLKHSHPNDD KDSGFFPRNP SSSSVNSVLG NHHPTPSHGP DGAVPTMADD QGEPAPLWPH 480
DPDAKEKPLH MPGGDGHRGK SLKLLEKIPE DAEATVVLVG CVPFLEQPAA AFVRLSEAVL 540
LESVLEVPVP VRFLFVMLGP SHTSTDYHEL GRSIATLMSD KLFHEAAYQA DDRQDLLGAI 600
SEFLDGSIVI PPSEVEGRDL LRSVAAFQRE LLRKRREREQ TKVEMTTRGG YAAPGKELSL 660
EMGGSEATSE DDPLQRTGSV FGGLVRDVKR RYPHYPSDLR DALHSQCVAA VLFIYFAALS 720
PAITFGGLLG EKTEGLMGVS ELIVSTAVLG VLFSLLGAQP LLVVGFSGPL LVFEEAFFKF 780
CRAQDLEYLT GRVWVGLWLV VFVLALVAAE GSFLVRYISP FTQEIFAFLI SLIFIYETFH 840
KLYKVFTEHP LLPFYPPDEA LETGLELNSS ALPPTEGPPG PRNQPNTALL SLILMLGTFL 900
IAFFLRKFRN SRFLGGKARR IIGDFGIPIS ILVMVLVDYS ITDTYTQKLT VPTGLSVTSP 960
HKRTWFIPPL GSARPFPPWM MVAAAVPALL VLILIFMETQ ITALIVSQKA RRLLKGSGFH 1020
LDLLLIGSLG GLCGLFGLPW LTAATVRSVT HVNALTVMRT AIAPGDKPQI QEVREQRVTG 1080
VLIASLVGLS IVMGAVLRRI PLAVLFGIFL YMGVTSLSGI QLSQRLLLIF MPAKHHPEQP 1140
YVTKVKTWRM HLFTCIQLGC IALLWVVKST AASLAFPFLL LLTVPLRRCL LPRLFQDREL 1200
QALDSEDAEP NFDEDGQDEY NELHMPV 1227 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IDA:MGI. GO:0015301; F:anion:anion antiporter activity; IDA:MGI. GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro. GO:0051453; P:regulation of intracellular pH; IDA:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |