CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019486
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 LisH domain-containing protein FOPNL 
Protein Synonyms/Alias
 FGFR1OP N-terminal-like protein; FOP-related protein of 20 kDa 
Gene Name
 FOPNL 
Gene Synonyms/Alias
 C16orf63; FOR20; PHSECRG2 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
8MATVAELKAVLKDTLubiquitination[1]
18LKDTLEKKGVLGHLKubiquitination[1]
128GIQNAFLKGPSLQPSubiquitination[1, 2]
155PMDDHLRKEEQKSTNubiquitination[1]
159HLRKEEQKSTNIEDLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
 Involved in the biogenesis of cilia. 
Sequence Annotation
 DOMAIN 49 81 LisH.
 REGION 1 104 Necessary and sufficient for  
Keyword
 Cell projection; Cilium biogenesis/degradation; Complete proteome; Cytoplasm; Cytoskeleton; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 174 AA 
Protein Sequence
MATVAELKAV LKDTLEKKGV LGHLKARIRA EVFNALDDDR EPRPSLSHEN LLINELIREY 60
LEFNKYKYTA SVLIAESGQP VVPLDRQFLI HELNAFEESK DNTIPLLYGI LAHFLRGTKD 120
GIQNAFLKGP SLQPSDPSLG RQPSRRKPMD DHLRKEEQKS TNIEDLHVSQ AVNR 174 
Gene Ontology
 GO:0034451; C:centriolar satellite; IDA:UniProtKB.
 GO:0005932; C:microtubule basal body; ISS:UniProtKB.
 GO:0031514; C:motile cilium; ISS:UniProtKB.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0042384; P:cilium assembly; IMP:UniProtKB.
 GO:0034453; P:microtubule anchoring; IEA:InterPro. 
Interpro
 IPR018993; FOP_dimerisation-dom_N.
 IPR006594; LisH_dimerisation. 
Pfam
 PF09398; FOP_dimer 
SMART
 SM00667; LisH 
PROSITE
 PS50896; LISH 
PRINTS