CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007214
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable proline--tRNA ligase, mitochondrial 
Protein Synonyms/Alias
 Altered inheritance rate of mitochondria protein 10; Prolyl-tRNA synthetase; ProRS 
Gene Name
 AIM10 
Gene Synonyms/Alias
 YER087W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
25SLSNNTLKSETTQELacetylation[1]
Reference
 [1] Preparative peptide isoelectric focusing as a tool for improving the identification of lysine-acetylated peptides from complex mixtures.
 Xie H, Bandhakavi S, Roe MR, Griffin TJ.
 J Proteome Res. 2007 May;6(5):2019-26. [PMID: 17397211
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Ligase; Mitochondrion; Nucleotide-binding; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 576 AA 
Protein Sequence
MLKYRTLSRS CHIFHPKSLS NNTLKSETTQ ELLQTVGFVR RSQVGLFQWL PLGLRSLNKV 60
SNAIRNRMDS DGGAIEVSLS AISSKALWQA TDRWNNSELF KLKDSKGKQY CLTATCEEDI 120
TDLMKNYIAS YKDMPITIYQ MTRKYRDEIR PRGGILRGRE FLMKDAYSFA SNEEDAFASF 180
QKLDDTYNKI FKDLKIPFVS AWADSGDIGG EFSKEFHLIH ESGEDTLMSC KHCGDISTLD 240
MSQSYPEKDG QYSGDVDCKY ALTKDHSTLI CFYYPKDRQL NWNLALNAMD KDIDLTLRNK 300
PNDHVLQVYE KDNEDIMFSK ILRVMDCRLN SKSNFPDFPL KKYLKNNFGQ ISDVSIVDAQ 360
ENEICGKCEE GRLEPLKSIE VGHIFLLGNK YSKPLNVKFV DKENKNETFV HMGCYGIGVS 420
RLVGAIAELG RDSNGFRWPA IMAPYKVSIC TGPNNPENSQ RLQDVKSELL NDPTMQNLQN 480
DILDQFNEKL GIGARIKLSH AMGIPLCVIV GSKSWPNVEI EVRGIRWGEK DLWRKQFEKR 540
CSELQWKCTK NEHGIEKHTV PIQHLAEVIG VLLKDM 576 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004827; F:proline-tRNA ligase activity; ISS:SGD.
 GO:0006433; P:prolyl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR002314; aa-tRNA-synt_IIb_cons-dom.
 IPR006195; aa-tRNA-synth_II.
 IPR004154; Anticodon-bd.
 IPR002316; Pro-tRNA-ligase_IIa.
 IPR004500; Pro-tRNA-synth_IIa_bac-type. 
Pfam
 PF00587; tRNA-synt_2b 
SMART
  
PROSITE
 PS50862; AA_TRNA_LIGASE_II 
PRINTS
 PR01046; TRNASYNTHPRO.