CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038487
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Cyp2c44 
Protein Synonyms/Alias
  
Gene Name
 Cyp2c44 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
60DIPASLSKLAKEYGPubiquitination[1]
112PIIEDSQKGHGIVFSubiquitination[1]
136RFSLMTLKNFGMGKRubiquitination[1]
142LKNFGMGKRSLEERVubiquitination[1]
251VKNFILEKVKEHQESubiquitination[1]
253NFILEKVKEHQESLDubiquitination[1]
274YIDCFLSKIEEEKHNubiquitination[1]
326KHPEVQAKVHEELDRubiquitination[1]
348PSMKDKMKLPYTDAVubiquitination[1]
379HAVVQDTKFRHYVIPubiquitination[1]
410KEFPNPEKFDPGHFLubiquitination[1]
419DPGHFLDKNGCFKKTubiquitination[1]
425DKNGCFKKTDYFVPFubiquitination[1]
436FVPFSLGKRSCVGEGubiquitination[1]
474EPKDLDIKPVTTGLFubiquitination[1]
488FNLPPPYKLRLVPR*ubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 494 AA 
Protein Sequence
MELLGLPTLA LLVLVMSLSL LSVWTKMRTG GRLPPGPTPL PIIGNILQLD LKDIPASLSK 60
LAKEYGPVYT LYFGSWPTVV LHGYDVVKEA LLNQGDEFLG RGPLPIIEDS QKGHGIVFSE 120
GERWKLLRRF SLMTLKNFGM GKRSLEERVQ EEARCLVEEL HKTEAQPFDP TFILACAPCN 180
VICSILFNER FPYNDKTFLN LMDLLNKNFY QLNSIWIQMY NLWPTIMKYI PGKHREFSKR 240
LGGVKNFILE KVKEHQESLD PANPRDYIDC FLSKIEEEKH NLKSDFNLEN LAICGSNLFT 300
AGTETTSTTL RFGLLLLVKH PEVQAKVHEE LDRVIGRHQP PSMKDKMKLP YTDAVLHEIQ 360
RYITLLPSSL PHAVVQDTKF RHYVIPKGTA VFPFLSSILL DQKEFPNPEK FDPGHFLDKN 420
GCFKKTDYFV PFSLGKRSCV GEGLARMELF LFFTTILQKF SLKALVEPKD LDIKPVTTGL 480
FNLPPPYKLR LVPR 494 
Gene Ontology
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. 
Interpro
 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR002401; Cyt_P450_E_grp-I.
 IPR008067; Cyt_P450_E_grp-I_CYP2A-like. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
 PS00086; CYTOCHROME_P450 
PRINTS
 PR00463; EP450I.
 PR01684; EP450ICYP2A.
 PR00385; P450.