UniProt Accession

 D3Z4I2_MOUSE; D3Z4I2 

Genbank Protein ID

 AC161765 

Genbank Nucleotide ID

  

Protein Name

 Glutaryl-CoA dehydrogenase, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 Gcdh 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
35	SAAAHTEKTQIRPAK	acetylation	[1]
51	SRPVFDWKDPLILEE	acetylation	[1, 2, 3]
51	SRPVFDWKDPLILEE	succinylation	[3]

Reference

 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 66 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0000062; F:fatty-acyl-CoA binding; IEA:Compara.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:Compara.
 GO:0004361; F:glutaryl-CoA dehydrogenase activity; IEA:Compara.
 GO:0019395; P:fatty acid oxidation; IEA:Compara.
 GO:0046949; P:fatty-acyl-CoA biosynthetic process; IEA:Compara. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS