CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044241
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 SET and MYND domain-containing protein 4 
Protein Synonyms/Alias
  
Gene Name
 SMYD4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
47GLCVDPLKGRCLVATubiquitination[1]
181LCDKISNKDICLPESubiquitination[1]
193PESNNQVKTLNYGLGubiquitination[1]
470QQVRVAQKLLRDGELubiquitination[1]
521AALGDWQKSATHLQRubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 558 AA 
Protein Sequence
KMQEKDSLTE SFPAALAKTL EDAALREENE QLSNASSSIG LCVDPLKGRC LVATKDILPG 60
ELLVQEDAFV SVLNPGELPP PHHGLDSKWD TRVTNGDLYC HRCLKHTLAT VPCDGCSYAK 120
YCSQECLQQA WELYHRTECP LGGLLLTLGV FCHIALRLTL LVGFEDVRKI ITKLCDKISN 180
KDICLPESNN QVKTLNYGLG ESEKNGNIVE TPIPGCDING KYENNYNAVF NLLPHTENHS 240
PEHKFLCALC VSALCRQLEA ASLQAIPTER IVNSSQLKAA VTPELCPDVT IWGVAMLRHM 300
LQLQCNAQAM TTIQHTGPKG SIVTDSRQVR LATGIFPVIS LLNHSCSPNT SVSFISTVAT 360
IRASQRIRKG QEILHCYGPH KSRMGVAERQ QKLRSQYFFD CACPACQTEA HRMAAGPRWE 420
AFCCNSCGAP MQGDDVLRCG SRSCAESAVS RDHLVSRLQD LQQQVRVAQK LLRDGELERA 480
VQRLSGCQRD AESFLWAEHA VVGEIADGLA RACAALGDWQ KSATHLQRSL YVVEVRHGPS 540
SVEMGHELFK LAQIFFNG 558 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001214; SET_dom.
 IPR002893; Znf_MYND. 
Pfam
 PF00856; SET
 PF01753; zf-MYND 
SMART
 SM00317; SET 
PROSITE
 PS50280; SET
 PS01360; ZF_MYND_1
 PS50865; ZF_MYND_2 
PRINTS