CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024467
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Putative Rab-43-like protein ENSP00000330714 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
37EIQGKRVKLQIWDTAubiquitination[1]
101VQLLIGNKSDLSELRubiquitination[2]
161GGPLFSEKSPDHIQLubiquitination[1, 2]
171DHIQLNSKDIGEGWGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
 NP_BIND 42 46 GTP (By similarity).
 NP_BIND 100 103 GTP (By similarity).
 MOTIF 16 24 Effector region (By similarity).
 MOD_RES 181 181 Cysteine methyl ester (By similarity).
 LIPID 179 179 S-geranylgeranyl cysteine (By
 LIPID 181 181 S-geranylgeranyl cysteine (By  
Keyword
 Complete proteome; GTP-binding; Lipoprotein; Methylation; Nucleotide-binding; Prenylation; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 181 AA 
Protein Sequence
MCVVQRFKTG AFSERQGSTI GVDFTMKTLE IQGKRVKLQI WDTAGQERFR TITQSYYRSA 60
NGAILAYDIT KRSSFLSVPH WIEDVRKYAG SNIVQLLIGN KSDLSELREV SLAEAQSLAE 120
HYDILCAIET SAKDSSNVEE AFLRVATELI MRHGGPLFSE KSPDHIQLNS KDIGEGWGCG 180
C 181 
Gene Ontology
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:InterPro.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003579; Small_GTPase_Rab_type. 
Pfam
 PF00071; Ras 
SMART
 SM00175; RAB 
PROSITE
 PS51419; RAB 
PRINTS
 PR00449; RASTRNSFRMNG.