CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023470
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RNA-binding protein 4F 
Protein Synonyms/Alias
  
Gene Name
 Rnp4F 
Gene Synonyms/Alias
 4f-rnp; CG3312 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
5***MDADKQLERQLEacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 May be involved in gene regulation during development. Binds RNA. 
Sequence Annotation
 DOMAIN 724 801 RRM.
 MOD_RES 43 43 Phosphoserine.
 MOD_RES 153 153 Phosphoserine.
 MOD_RES 713 713 Phosphoserine.
 MOD_RES 717 717 Phosphotyrosine.
 MOD_RES 718 718 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Developmental protein; Phosphoprotein; Reference proteome; RNA editing; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 941 AA 
Protein Sequence
MDADKQLERQ LEKELDEMPA EDLDDDAYDE YDLIVIPDQG KGSPQQGHSE SPQQEEEHKS 60
EELRQRSRPT WPPSSAGGDM TTIELISSDD EPSVEETEGG NAAGRGRARN DSSSSSDDVG 120
VIEGSELESN SEVSSDSDSD SDNAGGGNQL ERSYQELNAL PSKKFAQMVS LIGIAFKLND 180
LEKIESSVLE LQNLATVPAH VWLKYLKARL VVTQTDEERK AFEEQCAKAL GYYYSIPLSE 240
YVVNYLVDQG NVQNHVLWAK LLADYDVERP DFGDKLRSLI STITDENEAA AFVEMLQKHC 300
VTWTCNVEQR QMIKSVVDKF KQHLDETTRG WDWSEQHKAH VYDVETLSLD DDLKNAVIRF 360
IFERSVAKFP IVDVLWLSYI EFIQFEGVTV PENEDENEVT AEMVAKRAKR LGKGFLRNTE 420
LDLANRGVRS HPSVQLNHRF LDLMERSDFE LAEVDEEIRL ILQRIVTDMD MTVELHLDYL 480
AYRIRNTNAS DEQQVASLRA AFNHAWEELT VLYGDQADTR YEVLQLWAQV EYTQLGSPDN 540
GREIWRQIMG YPGSSIRGLL WLNFAQMESE YNGGHGTRDV LRKALSQPVL ENGLMVQEFF 600
RRYERCYGTY ESIAACQALD LPVEYVKPRS RIKPNSQSAY PRQQKLKPRQ QQQQTNREPL 660
NREQRRRQAH EQQQQQQQQQ KHGIKKSRTE PSGGATSPPS KVKGPANAEA KESNFKYSPN 720
MEINKIFVRN LHPACSKEEL HELFSPFGTI KDVRLVHKLN KQFKGIAYVE FEKPGEAQRA 780
VAGRDGCLFK GMNISVAISN PPPRGTSAVK PSVAPKRRVP TSLIPTTLVR QEVAAKKLRL 840
LLPEPGDISS TSASVDVAIK REANGEEQKG DVQERDEQKG EEQKGEEQKG EEPKGEEQKG 900
DDQIGEEQSG VEQKGDEKKE EEMPAAVPKS NDDFRKLFLK D 941 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003729; F:mRNA binding; ISS:FlyBase.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0007417; P:central nervous system development; IMP:FlyBase.
 GO:0006396; P:RNA processing; IEA:InterPro. 
Interpro
 IPR003107; HAT.
 IPR008669; LSM_interact.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF05391; Lsm_interact
 PF00076; RRM_1 
SMART
 SM00386; HAT
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS