| Tag | Content |
|---|
| CPLM ID | CPLM-017264 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 131 |
Protein Synonyms/Alias | |
Gene Name | Znf131 |
Gene Synonyms/Alias | Zfp131 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 49 | GHHFKAHKAVLAACS | acetylation | [1] | | 61 | ACSKFFYKFFQEFTQ | acetylation | [1] |
|
Reference | [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation. Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ. J Biol Chem. 2013 Jul 17;. [ PMID: 23864654] |
Functional Description | May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling (By similarity). Plays a role during development and organogenesis as well as in the function of the adult central nervous system. |
Sequence Annotation | DOMAIN 34 98 BTB.
ZN_FING 261 283 C2H2-type 1.
ZN_FING 288 311 C2H2-type 2.
ZN_FING 328 350 C2H2-type 3.
ZN_FING 356 381 C2H2-type 4; degenerate.
ZN_FING 392 414 C2H2-type 5.
ZN_FING 420 443 C2H2-type 6.
MOTIF 137 148 Nuclear localization signal 1 (By
MOTIF 317 328 Nuclear localization signal 2 (By
CROSSLNK 598 598 Glycyl lysine isopeptide (Lys-Gly) |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Isopeptide bond; Metal-binding; Nucleus; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation; Ubl conjugation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 619 AA |
Protein Sequence | MEAEETMECL QEFPEHHKMI LDRLNEQREQ DRFTDITLIV DGHHFKAHKA VLAACSKFFY 60
KFFQEFTQEP LVEIEGVSKM AFRHLIEFTY TAKLMIQGEE EANDVWKAAE FLQMLEAIKA 120
LEVRNKENSA PLEENTTGKN EAKKRKIAET SNVITESLPS AESEPVEIEV EIAEGTIEVE 180
DEGIEALEEM ASAKQSIKYI QSTGSSDDSA LALLADITSK YRQGESKGQI SEDDCASDPI 240
SKQVEGIEIV ELQLSHVKDL FHCEKCNRSF KLFYHFKEHM KSHSTESFKC EICNKRYLRE 300
SAWKQHLNCY HLEEGGVSKK QRTGKKIHIC QYCDKQFDHF GHFKEHLRKH TGEKPFECSN 360
CHERFARNST LKCHLTACQT GVGAKKGRKK LYECQVCNSV FNSWDQFKDH LVIHTGDKPN 420
HCTLCDLWFM QGNELRRHLS DAHNISERIV TEEVLSVETH LQTEPVTSMT IIEQVGKVHV 480
LPLLQVQVDS AQVTVEQVHP DLLQDSQVHD SQMTGLPEQV QVSYLEVGRI QTEEGTEVHV 540
EELHVERVNQ MPVEVQTELL EADLDHMTPE IMSQEEREPN HADAAMEEHE DAEGLETKPS 600
EYSQARKTEN DRTSLPVLE 619 |
Gene Ontology | GO:0005634; C:nucleus; IBA:RefGenome. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome. GO:0008270; F:zinc ion binding; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |