CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017798
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 FAD synthase 
Protein Synonyms/Alias
 FAD pyrophosphorylase; FMN adenylyltransferase; Flavin adenine dinucleotide synthase; Molybdenum cofactor biosynthesis protein-like region; FAD synthase region 
Gene Name
 Flad1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
273KAGEAVYKLAESGSCubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme (By similarity). 
Sequence Annotation
 REGION 19 110 Molybdenum cofactor biosynthesis protein-
 REGION 303 460 FAD synthase.
 MOD_RES 468 468 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; ATP-binding; Complete proteome; Direct protein sequencing; FAD; FMN; Nucleotide-binding; Nucleotidyltransferase; Phosphoprotein; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 492 AA 
Protein Sequence
MASRASELPP GSGRSVTAGI IIVGDEILKG HTQDTNTYFL CRTLRSLGVQ VCRVSVVPDE 60
VATIASEVNS FSRRFTHVLT AGGIGPTHDD VTFEAVAQAF GEELKPHPEL QAAIKTLGGE 120
GWEKLSMVPS SARLHYGTDP RTGHPFRFPL VSVRNVYLFP GIPELLRRVL EGLKGLFQNT 180
AVQFHLKELY VAASEGSIAP ILSEAQAHFG RRLSLGSYPD WSSNYFQVKL ILDSEEKEPL 240
EECLAYLTAR LPQGSLVPYQ PDAVEKAGEA VYKLAESGSC LGKKVAGALQ TIETALAQYH 300
LSQLCVGFNG GKDCTALLHL FHAAVQRKFP DVPKPLQILY IRSISPFPEL EQFLQDTIKR 360
YNLQVLEAEG NMKQALGELQ EKHPQLEAVL MGTRRTDPYS CSLSHFSPTD PGWPSFMRIN 420
PLLDWTYRNI WEFLRQLFVP YCILYDRGYT SLGSRENTTQ NPALKCLSPG GHPVYRPAYL 480
LENEDEERNS RIPKTPGASW PSPRMGHKEL KKEPRTLL 518 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003919; F:FMN adenylyltransferase activity; IEA:EC.
 GO:0006747; P:FAD biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:InterPro. 
Interpro
 IPR012183; FAD_synth_Mopterin-bd.
 IPR001453; Mopterin-bd_dom.
 IPR002500; PAPS_reduct.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF00994; MoCF_biosynth
 PF01507; PAPS_reduct 
SMART
 SM00852; MoCF_biosynth 
PROSITE
  
PRINTS