CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024241
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transaldolase 
Protein Synonyms/Alias
  
Gene Name
 tal 
Gene Synonyms/Alias
 MSMEG_3102; MSMEI_3024 
Created Date
 July 27, 2013 
Organism
 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
NCBI Taxa ID
 246196 
Lysine Modification
Position
Peptide
Type
References
132LQAIELWKIVDRPNLpupylation[1]
219EIDARLEKIGSDEALpupylation[2]
Reference
 [1] Expansion of the mycobacterial "PUPylome".
 Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE 3rd, Bark S, Dorrestein PC.
 Mol Biosyst. 2010 Feb;6(2):376-85. [PMID: 20094657]
 [2] Proteome-wide identification of mycobacterial pupylation targets.
 Poulsen C, Akhter Y, Jeon AH, Schmitt-Ulms G, Meyer HE, Stefanski A, Stühler K, Wilmanns M, Song YH.
 Mol Syst Biol. 2010 Jul 13;6:386. [PMID: 20631680] 
Functional Description
 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity). 
Sequence Annotation
 ACT_SITE 142 142 Schiff-base intermediate with substrate
 CROSSLNK 132 132 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Complete proteome; Cytoplasm; Isopeptide bond; Pentose shunt; Reference proteome; Schiff base; Transferase; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 371 AA 
Protein Sequence
MAQNPNLAAL SAAGVSVWLD DLSRDRLQTG NLTELINTRS VVGVTTNPSI FQAALSKGTA 60
YDAQVNELAA RGADVDATIR TVTTDDVRNA CDLLAKEYEA SDGVDGRVSI EVDPRLAHDT 120
DKTILQAIEL WKIVDRPNLL IKIPATMAGL PAISAVIAEG ISVNVTLIFS VERHRLVMDA 180
YLEGLEKAKE AGHDLSKIHS VASFFVSRVD TEIDARLEKI GSDEALALRG KAGVANARLA 240
YAAYEEVFGS DRFAKLKADG ARVQRPLWAS TGVKNPEYSD TLYVTELVAP NTVNTMPEKT 300
LEAVADHGEI TGNTIAGTAA SSQETFDKLA AIGIDLPDVF RVLEDEGVEK FEKSWQELLD 360
ATQGQLDAAK K 371 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004801; F:sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity; IEA:HAMAP.
 GO:0006098; P:pentose-phosphate shunt; IEA:HAMAP. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR001585; Transaldolase.
 IPR004732; Transaldolase_2.
 IPR018225; Transaldolase_AS. 
Pfam
 PF00923; Transaldolase 
SMART
  
PROSITE
 PS01054; TRANSALDOLASE_1
 PS00958; TRANSALDOLASE_2 
PRINTS