CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031514
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ58224, highly similar to Calpain-2 catalytic subunit (EC 3.4.22.53) 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
26GSHERAIKYLNQDYEubiquitination[1]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 523 AA 
Protein Sequence
MAGIAAKLAK DREAAEGLGS HERAIKYLNQ DYEALRNECL EAGTLFQDPS FPAIPSALGF 60
KELGPYSSKT RGIEWKRPTE ICADPQFIIG GAEEVESNGS LQKLIRIRNP WGEVEWTGRW 120
NDNCPSWNTI DPEERERLTR RHEDGEFWMS FSDFLRHYSR LEICNLTPDT LTSDTYKKWK 180
LTKMDGNWRR GSTAGGCRNY PNTFWMNPQY LIKLEEEDED EEDGESGCTF LVGLIQKHRR 240
RQRKMGEDMH AIGFGIYEVP EELSGQTNIH LSKNFFLTNR ARERSDTFIN LREVLNRFKL 300
PPGEYILVPS TFEPNKDGDF CIRVFSEKKA DYQAVDDEIE ANLEEFDISE DDIGDGFRRL 360
FAQLAGEDAE ISAFELQTIL RRVLAKRQDI KSDGFSIETC KIMVDMLDSD GSGKLGLKEF 420
YILWTKIQKY QKIYREIDVD RSGTMNSYEM RKALEEAGFK MPCQLHQVIV ARFADDQLII 480
DFDNFVRCLV RLETLFKIFK QLDPENTGTI ELDLISWLCF SVL 523 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR022684; Calpain_cysteine_protease.
 IPR022682; Calpain_domain_III.
 IPR022683; Calpain_III.
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR001300; Peptidase_C2_calpain_cat. 
Pfam
 PF01067; Calpain_III
 PF00648; Peptidase_C2 
SMART
 SM00720; calpain_III
 SM00230; CysPc
 SM00054; EFh 
PROSITE
 PS50203; CALPAIN_CAT
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS
 PR00704; CALPAIN.