CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006796
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized HTH-type transcriptional regulator YfhH 
Protein Synonyms/Alias
  
Gene Name
 yfhH 
Gene Synonyms/Alias
 b2561; JW2545 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
53VSQSSVVKFAQKLGYacetylation[1]
101PLRLVGEKLIKENTAacetylation[1]
279RHSEALVKKLV****acetylation[1]
280HSEALVKKLV*****acetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
  
Sequence Annotation
 DOMAIN 1 77 HTH rpiR-type.
 DOMAIN 125 265 SIS.
 DNA_BIND 37 56 H-T-H motif (Potential).  
Keyword
 Complete proteome; DNA-binding; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 282 AA 
Protein Sequence
MNGLLRIRQR YQGLAQSDKK LADYLLLQPD TARHLSSQQL ANEAGVSQSS VVKFAQKLGY 60
KGFPALKLAL SEALASQPES PSVPIHNQIR GDDPLRLVGE KLIKENTAAM YATLNVNSEE 120
KLHECVTMLR SARRIILTGI GASGLVAQNF AWKLMKIGFN AAAVRDMHAL LATVQASSPD 180
DLLLAISYTG VRRELNLAAD EMLRVGGKVL AITGFTPNAL QQRASHCLYT IAEEQATNSA 240
SISACHAQGM LTDLLFIALI QQDLELAPER IRHSEALVKK LV 282 
Gene Ontology
 GO:0030246; F:carbohydrate binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR000281; HTH_RpiR.
 IPR001347; SIS.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF01418; HTH_6
 PF01380; SIS 
SMART
  
PROSITE
 PS51071; HTH_RPIR
 PS51464; SIS 
PRINTS