CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016516
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pleckstrin homology domain-containing family M member 3 
Protein Synonyms/Alias
 PH domain-containing family M member 3 
Gene Name
 Plekhm3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
92AQNVFPAKEQLMVQRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 DOMAIN 212 309 PH 1.
 DOMAIN 361 456 PH 2.
 ZN_FING 669 722 Phorbol-ester/DAG-type.
 MOD_RES 132 132 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Metal-binding; Phosphoprotein; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 761 AA 
Protein Sequence
MEALEVDDIS PALEVTEDFF STFDSKLEKA VQQAEVYGIQ EVPELVGHEV LGNIADNGAL 60
RSVASLGKGT MIWDHCKSRL LETKAQNVFP AKEQLMVQRG TAPDNLSWMA QKEASTFNFF 120
NICQRRRDRP RSVNDLLDET TTFKPGHARS RSDVTHVDWR VVLSTMPLQQ QQQQQQASLQ 180
GIHFPGPSFL LSSPSKVEDA QGNTEHKQTF PNILKKGYLE IRKNHDSYWQ SCYAELSPYN 240
LNFYSLDSSG NQNLYATYQL SHFQSISVLG NLEARMVDTV LYDNSQLQLK AESPWEALDW 300
GQKLWEVVHA AVPNYMGRQG EMANSPGLIH HGDCAQNHCL QKKSSGLLAS PVLDSPKQYQ 360
NILKSGTLYR LTVQNNWKAF TFVLSKAYLM AFHPGKLDED PLLSYNVDVC LAVQIDNLDG 420
CDSCFQVIFP QDVLRLRAET RQRAQEWMEA LKTAANAARS SEQNLQVTLR NKPKDQLDGR 480
ELRKNKRQSV TTSFLSILTT LSLERGLTAQ SFKCAGCQRS IGLSNGKAKV CNYSGWYYCS 540
SCHVDDSFLI PARIVHNWDT SKYKVSKQAK EFLEYVYEEP LIDIQQENPM LYLHAEPLAT 600
VVRLRQRLKS LRAYLFSCRA AVAEDLRRRI FPREYLLQQI HLYSLADLQQ VIEGKLAPFL 660
GKVIKFATAH VYSCSLCSQK GFICEICNNG EILYPFEDIS TSRCESCGAV FHSECKEKSV 720
PCPRCVRREL QKKQKSFWRQ LNVDESLEEA CAMFELSYQS T 761 
Gene Ontology
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro. 
Interpro
 IPR025258; DUF4206.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR002219; Prot_Kinase_C-like_PE/DAG-bd. 
Pfam
 PF13901; DUF4206
 PF00169; PH 
SMART
 SM00109; C1
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN
 PS00479; ZF_DAG_PE_1
 PS50081; ZF_DAG_PE_2 
PRINTS