UniProt Accession

 B3KPJ4_HUMAN; B3KPJ4 

Genbank Protein ID

 AL138837; AL513327; AK056429 

Genbank Nucleotide ID

 BAG51706.1 

Protein Name

 Polyhomeotic-like protein 2 

Protein Synonyms/Alias

 cDNA FLJ31867 fis, clone NT2RP7001856, highly similar to Polyhomeotic-like protein 2 

Gene Name

 PHC2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
238	EPYLQESKEEGAPLK	ubiquitination	[1, 2]
259	GRVDFAYKFKRSKRF	acetylation	[3]
399	FLPSEPTKWNVEDVY	ubiquitination	[1, 2]
436	GQALLLLKEDHLMSA	ubiquitination	[2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 464 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:HPA.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 

Interpro

 IPR001660; SAM.
 IPR013761; SAM/pointed.
 IPR021129; SAM_type1.
 IPR012313; Znf_FCS. 

Pfam

 PF00536; SAM_1 

SMART

 SM00454; SAM 

PROSITE

 PS50105; SAM_DOMAIN
 PS51024; ZF_FCS 

PRINTS