CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011781
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative serine/threonine-protein kinase YPL150W 
Protein Synonyms/Alias
  
Gene Name
 YPL150W 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
325RRLLKRLKQSGVDTQubiquitination[1]
413SLSKMLNKGSDFVTSubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Putative serine/threonine-protein kinase (By similarity). 
Sequence Annotation
 DOMAIN 41 287 Protein kinase.
 NP_BIND 47 55 ATP (By similarity).
 ACT_SITE 157 157 Proton acceptor (By similarity).
 BINDING 70 70 ATP (By similarity).
 MOD_RES 456 456 Phosphoserine.
 MOD_RES 533 533 Phosphoserine.  
Keyword
 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 901 AA 
Protein Sequence
MVNPVGSSKL EQNNIKSIIG SSYNRLYSQF TSDELTEVGN YKILKQIGEG SFGKVYLALH 60
RPTHRKVCLK TSDKNDPNIV REVFYHRQFD FPYITKLYEV IVTESKVWMA LEYCPGKELY 120
DHLLSLRRIS LLECGELFAQ ISGAVYYAHS MHCVHRDLKL ENILLDKNGN AKLTDFGFTR 180
ECMTKTTLET VCGTTVYMAP ELIERRTYDG FKIDIWSLGV ILYTLITGYL PFDDDDEAKT 240
KWKIVNEEPK YDAKVIPDDA RDLISRLLAK NPGERPSLSQ VLRHPFLQPY GSVVLDQTQK 300
ILCRQRSGGT QFKSKLERRL LKRLKQSGVD TQAIKQSILK KKCDSLSGLW LLLLAQGKKQ 360
ENCKYPKRSR SVLSVKKVIE SATHNDTNGI SEDVLKPSLE LSRAASLSKM LNKGSDFVTS 420
MTPVSRKKSK DSAKVLNPTL SKISSQRAYS HSIAGSPRKS NNFLQKVSSF FKSKKSSNSN 480
SNNSIHTNVS ESLIASNRGA PSSGSFLKKN SGSIQKSRTD TVANPSRTES IGSLNENVAG 540
AIVPRSANNT TLENKKTSGN EIGLKVAPEL LLNEHIRIEE PRLKRFKSSI SSEISQTSTG 600
NYDSESAENS RSISFDGKVS PPPIRNRPLS EISQISNDTY ISEYSTDGNN SSFKISDTIK 660
PSYIRKGSET TSQYSASSEK MTNGYGRKFV RRDLSIVSTA SSTSERSSRT DSFYDITTAT 720
PVVTTDNRRN KNNNLKESVL PRFGTQRPWT GKRTYTTSRH GKNARRSSKR GLFKITSSNT 780
DSIIQEVSSS EEEDHNVIYS KGKGLPTPVL QTKGLIENGL NERDEEGDDE YAIHTDGEFS 840
IKPQFSDDVI DKQNHLPSVK AVATKRSLSE GSNWSSSYLD SDNNRRRVSS LLVEDGGNPT 900
A 901 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004672; F:protein kinase activity; IDA:SGD.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00069; Pkinase 
SMART
 SM00220; S_TKc 
PROSITE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS