| Tag | Content |
|---|
| CPLM ID | CPLM-017887 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | TBC1 domain family member 22A |
Protein Synonyms/Alias | |
Gene Name | Tbc1d22a |
Gene Synonyms/Alias | D15Ertd781e |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 221 | TDLEELRKLSWSGIP | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May act as a GTPase-activating protein for Rab family protein(s) (By similarity). |
Sequence Annotation | DOMAIN 221 445 Rab-GAP TBC. |
Keyword | Alternative splicing; Complete proteome; GTPase activation; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 516 AA |
Protein Sequence | MRSGHGQRRG QEAVLEAQQQ QGSRAASSMC MEPSTHRLIR CYMAPCLKST PKVPTTPVKA 60
KRVSTFQEFE SNTSDAWDAG EDDDELLAMA TESLNSEVVM ETAHRVLRNH SQRQSQPSQK 120
TTEPEPEPQP IAEPPVPPSG DLRLVKSVSE SHTPCPSEST GDTVPLQRSQ SLPHSATVTL 180
SGTSDPHALA DSALSKRETS RLDKFKQLLA GPNTDLEELR KLSWSGIPKP VRPMTWKLLS 240
GYLPANVDRR PATLQRKQKE YFAFIEHYYS SRNDEVHQDT YRQIHIDIPR MSPEALILQP 300
KVTEIFERIL FIWAIRHPAS GYVQGINDLV TPFFVVFICE YTDREDVDKV DVSSVPAEVL 360
RNIEADTYWC MSKLLDGIQD NYTFAQPGIQ MKVKMLEELV SRIDERVHRH LDGHEVRYLQ 420
FAFRWMNNLL MRELPLRCTI RLWDTYQSEP EGFSHFHLYV CAAFLVRWRR EILEERDFQE 480
LLLFLQNLPT ARWDDQDVSL LLAEAYRLKF AFADAPNHYK K 521 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |