| Tag | Content |
|---|
| CPLM ID | CPLM-011073 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vacuolar protein sorting-associated protein 72 |
Protein Synonyms/Alias | SWR complex protein 2 |
Gene Name | VPS72 |
Gene Synonyms/Alias | SWC2; YDR485C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 33 | NAGNKLQKLLEQELR | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Participates in the catalytic exchange of histone H2A for the H2A variant HTZ1, an euchromatin-specific factor, leading to chromatin remodeling and changes in transcription of targeted genes. Indirectly involved in vacuolar protein sorting. |
Sequence Annotation | REGION 1 281 Interaction with HTZ1.
MOD_RES 425 425 Phosphoserine. |
Keyword | Chromatin regulator; Coiled coil; Complete proteome; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 795 AA |
Protein Sequence | MSDEGADKSL DTNTEFIIQT RSRRSNAGNK LQKLLEQELR DIESTKRQIS SYKNGNDDEE 60
DEIGLLFQED EDDEDFEMMA KDDDDEGEEK EDETQSIRKE PSQASSEQAA DDLMFSSSES 120
EDSSNENDED AEEKEIRRQE LLSRKKRNKR LQKGPVVIKK QKPKPKSGEA IPRSHHTHEQ 180
LNAETLLLNT RRTSKRSSVM ENTMKVYEKL SKAEKKRKII QERIRKHKEQ ESQHMLTQEE 240
RLRIAKETEK LNILSLDKFK EQEVWKKENR LALQKRQKQK FQPNETILQF LSTAWLMTPA 300
MELEDRKYWQ EQLNKRDKKK KKYPRKPKKN LNLGKQDASD DKKRESEESI KNDGDVNSLG 360
ENSSSVHNQK RIEETSTNDT VEGESSPDAA VSRVNSDELK PTALPDVTLD AIANKQSTVD 420
EAPNSQPQKN IITNEQKITN VGEPIQNLHN EEIKDEMVSA LESRENTFEN SSPAAQVVSQ 480
RDNSATPTPS NSTGTEDTIL ISPDTDIKGE PEPCLKTEGI ENLSHNVPQE TKSNTDVSFL 540
KQVTFTDHPQ VAIIDTEESP SKKDTANVDE SSAENSLSTQ TYEGPEQLTS RNFVTLYDFP 600
NAPPNLKDFN TNLFGDRWSY TNGLSATQRP QDMKTVFHSI LPSPPQSSVP SPTVDISLDL 660
SALANFPSFG EYDKKIVHQI NTEINKDLEI KIKTQPPTGV FLANGIRKKC LITNKECQYF 720
DPRTGVPYSD VEAYKIIQRI QDPISKEEGR SDIKRDETTN EDSDDQVRFK WFGFKNGGIY 780
LDLSQRPAKG VPEGF 795 |
Gene Ontology | |
Interpro | |
Pfam | |
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PROSITE | |
PRINTS | |