CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026238
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Dehydrodolichyl diphosphate synthase 
Protein Synonyms/Alias
  
Gene Name
 DHDDS 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
156FLQALELKRADWLARubiquitination[1, 2, 3, 4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 169 AA 
Protein Sequence
LARQKFSRLM EEKEKLQKHG VCIRVLGDLH LLPLDLQELI AQAVQATKNY NNDISESLLD 60
KCLYTNRSPH PDILIRTSGE VRLSDFLLWQ QKARDMYAEE RKRQQLERDQ ATVTEQLLRE 120
GLQASGDAQL RRTRLHKLSA RREERVQGFL QALELKRADW LARLGTASA 169 
Gene Ontology
 GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro. 
Interpro
 IPR001441; UPP_synth-like.
 IPR018520; UPP_synth-like_CS. 
Pfam
 PF01255; Prenyltransf 
SMART
  
PROSITE
 PS01066; UPP_SYNTHASE 
PRINTS