CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007433
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sorting nexin MVP1 
Protein Synonyms/Alias
  
Gene Name
 MVP1 
Gene Synonyms/Alias
 YMR004W; YM8270.06 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
98ANETVIDKNDARDQNubiquitination[1]
422KEKLESMKGKPDVSGubiquitination[1]
424KLESMKGKPDVSGAEubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Required for vacuolar protein sorting. 
Sequence Annotation
 DOMAIN 128 247 PX.
 BINDING 172 172 Phosphatidylinositol 3-phosphate (By
 BINDING 174 174 Phosphatidylinositol 3-phosphate; via
 BINDING 198 198 Phosphatidylinositol 3-phosphate (By
 BINDING 213 213 Phosphatidylinositol 3-phosphate (By  
Keyword
 Complete proteome; Cytoplasm; Membrane; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 511 AA 
Protein Sequence
MDNYEGSDPW NTSSNAWTKD DDHVVSTTNS EPSLNGISGE FNTLNFSTPL DTNEEDTGFL 60
PTNDVLEESI WDDSRNPLGA TGMSQTPNIA ANETVIDKND ARDQNIEESE ADLLDWTNNV 120
RKTYRPLDAD IIIIEEIPER EGLLFKHANY LVKHLIALPS TSPSEERTVV RRYSDFLWLR 180
EILLKRYPFR MIPELPPKRI GSQNADQLFL KKRRIGLSRF INLVMKHPKL SNDDLVLTFL 240
TVRTDLTSWR KQATYDTSNE FADKKISQEF MKMWKKEFAE QWNQAASCID TSMELWYRIT 300
LLLERHEKRI MQMVHERNFF ETLVDNFSEV TPKLYPVQQN DTILDINNNL SIIKKHLETT 360
SSICKQETEE ISGTLSPKFK IFTDILLSLR SLFERYKIMA ANNVVELQRH VELNKEKLES 420
MKGKPDVSGA EYDRIKKIIQ KDRRSIIEQS NRAWLIRQCI LEEFTIFQET QFLITRAFQD 480
WAKLNSNHAG LKLNEWEKLV TSIMDMPISR E 511 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.
 GO:0007154; P:cell communication; IEA:InterPro.
 GO:0006623; P:protein targeting to vacuole; IMP:SGD. 
Interpro
 IPR001683; Phox. 
Pfam
 PF00787; PX 
SMART
 SM00312; PX 
PROSITE
 PS50195; PX 
PRINTS