UniProt Accession

 STX3_MOUSE; Q64704 

Genbank Protein ID

 D29797; D29798; D29799; D29800; D38375 

Genbank Nucleotide ID

 BAA06180.1; BAA06181.1; BAA06182.1; BAA06183.1; BAA07454.1 

Protein Name

 Syntaxin-3 

Protein Synonyms/Alias

  

Gene Name

 Stx3 

Gene Synonyms/Alias

 Stx3a 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
58	EHVEEAKKLYSIILS	ubiquitination	[1]
100	NKLKSMEKHIEEDEV	acetylation	[2]
100	NKLKSMEKHIEEDEV	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379] 

Functional Description

 Potentially involved in docking of synaptic vesicles at presynaptic active zones. 

Sequence Annotation

 DOMAIN 191 253 t-SNARE coiled-coil homology.  

Keyword

 Alternative splicing; Coiled coil; Complete proteome; Membrane; Neurotransmitter transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 289 AA 

Protein Sequence

Gene Ontology

 GO:0016324; C:apical plasma membrane; IDA:MGI.
 GO:0042582; C:azurophil granule; IEA:Compara.
 GO:0005911; C:cell-cell junction; IEA:Compara.
 GO:0030426; C:growth cone; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0030141; C:secretory granule; IDA:MGI.
 GO:0031201; C:SNARE complex; IEA:Compara.
 GO:0042581; C:specific granule; IEA:Compara.
 GO:0050544; F:arachidonic acid binding; IEA:Compara.
 GO:0006944; P:cellular membrane fusion; IEA:Compara.
 GO:0034599; P:cellular response to oxidative stress; IEA:Compara.
 GO:0006887; P:exocytosis; IMP:MGI.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0031175; P:neuron projection development; IEA:Compara.
 GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW. 

Interpro

 IPR015708; Syntaxin-3.
 IPR006012; Syntaxin/epimorphin_CS.
 IPR006011; Syntaxin_N.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 

Pfam

 PF05739; SNARE
 PF00804; Syntaxin 

SMART

 SM00503; SynN
 SM00397; t_SNARE 

PROSITE

 PS00914; SYNTAXIN
 PS50192; T_SNARE 

PRINTS