Tag | Content |
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CPLM ID | CPLM-003143 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Spermidine N(1)-acetyltransferase |
Protein Synonyms/Alias | Diamine acetyltransferase; SAT |
Gene Name | speG |
Gene Synonyms/Alias | b1584; JW1576 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
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68 | VVECDGEKAGLVELV | acetylation | [1] | 97 | ISPEYQGKGLATRAA | acetylation | [1] | 105 | GLATRAAKLAMDYGF | acetylation | [1] | 126 | KLYLIVDKENEKAIH | acetylation | [1] | 130 | IVDKENEKAIHIYRK | acetylation | [1] | 174 | HQYLAEHKTPGQTLL | acetylation | [1] | 182 | TPGQTLLKPTAQ*** | acetylation | [1] |
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Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Regulates polyamine concentration by their degradation. Acts on spermidine, forming N(1)- and N(8)-acetylspermidine. |
Sequence Annotation | DOMAIN 7 167 N-acetyltransferase. |
Keyword | Acyltransferase; Complete proteome; Cytoplasm; Direct protein sequencing; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 186 AA |
Protein Sequence | MPSAHSVKLR PLEREDLRYV HQLDNNASVM RYWFEEPYEA FVELSDLYDK HIHDQSERRF 60 VVECDGEKAG LVELVEINHV HRRAEFQIII SPEYQGKGLA TRAAKLAMDY GFTVLNLYKL 120 YLIVDKENEK AIHIYRKLGF SVEGELMHEF FINGQYRNAI RMCIFQHQYL AEHKTPGQTL 180 LKPTAQ 186 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004145; F:diamine N-acetyltransferase activity; IEA:EC. |
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