| Tag | Content |
|---|
| CPLM ID | CPLM-014218 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Probable palmitoyltransferase ZDHHC8 |
Protein Synonyms/Alias | Zinc finger DHHC domain-containing protein 8; DHHC-8 |
Gene Name | Zdhhc8 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 224 | TNEQVTGKFRGGVNP | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1. |
Sequence Annotation | ZN_FING 104 154 DHHC-type.
ACT_SITE 134 134 S-palmitoyl cysteine intermediate (By
MOD_RES 335 335 Phosphoserine.
MOD_RES 672 672 Phosphoserine. |
Keyword | Acyltransferase; Complete proteome; Cytoplasmic vesicle; Membrane; Metal-binding; Phosphoprotein; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 762 AA |
Protein Sequence | MPRSPGTRLK PAKYIPVATA AALLVGSSTL FFVFTCPWLT RAVSPAIPVY NGILFLFVLA 60
NFSMATFMDP GVFPRADEDE DKEDDFRAPL YKNVDVRGIQ VRMKWCATCH FYRPPRCSHC 120
SVCDNCVEDF DHHCPWVNNC IGRRNYRYFF LFLLSLSAHM VGVVAFGLLY VLNHSEGLGA 180
AHTTITMAVM CVAGLFFIPV IGLTGFHVVL VTRGRTTNEQ VTGKFRGGVN PFTRGCYGNV 240
EHVLCSPLAP RYVVEPPRMP LSVSLKPPFL RPELLERAVP LKVKLSDNGL KAGRSKSKGS 300
LDQLDEKPLD LGPPLPPKIE AGTFGRDLKT PRPGSAESAL SVQRTSPPTP AMYKFRPAFS 360
TGPKTPFCGP NEQVPGPDSL TLADDSTHSL DFVSEPSLDL PDHGPGGLRP PYPPSPPLNT 420
TDAFSGALRS LSLKAASRRG GDHMTLQPLR SEGGPPTPHR SLFAPHALPN RNGSLSYDSL 480
LNPGSPSGHA CPTHPSVGIA SYHSPYLHPG PSDPPRPPPR SFSPVLGPRP REPSPVRYDN 540
LSRTIMASIQ ERKDREERER LLRSQTDSLF GDSGVYDTPS SYSLQQASVL TEGPRGSVLR 600
YGSRDDLVAG PGFGGARNPA LQTSLSSLSS SMSRAPRTSS SSLQADQANN NAPGPRPGSG 660
SHRSPARQGL PSPPGTPRSP SYTGSKAVAF IHTDLPDRQP SLAMQRDHPQ LKTPPSKLNG 720
QSPGMARLGP AASPMGPNAS PARHTLVKKV SGVGGTTYEI SV 762 |
Gene Ontology | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005739; C:mitochondrion; IDA:MGI. GO:0048471; C:perinuclear region of cytoplasm; ISA:MGI. GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0007626; P:locomotory behavior; IMP:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |