CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045327
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Heterogeneous nuclear ribonucleoprotein M 
Protein Synonyms/Alias
  
Gene Name
 HNRNPM 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
71MDERALPKGDFFPPEubiquitination[1, 2]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 383 AA 
Protein Sequence
XGWKKLKEVF SMAGVVVRAD ILEDKDGKSR GIGTVTFEQS IEAVQAISMF NGQLLFDRPM 60
HVKMDERALP KGDFFPPERP QQLPHGLGGI GMGLGPGGQP IDANHLNKGI GMGNIGPAGM 120
GMEGIGFGIN KMGGMEGPFG GGMENMGRFG SGMNMGRING GGGGSVPGIE RMGPGIDRLG 180
GAGMERMGAG LGHGMDRVGS EIERMGLVMD RMGSVERMGS GIERMGPLGL DHMASSIERM 240
GQTMERIGSG VERMGAGMGF GLERMAAPID RVGQTIERMG SGVERMGPAI ERMGLSMERM 300
VPAGMGAGLE RMGPVMDRMA TGLERMGANN LERMGLERMG ANSLERMGLE RMGANSLERM 360
GPAMGPALGA GIERMGLAMG GGG 383 
Gene Ontology
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro. 
Interpro
 IPR024667; HnRNP_M.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS