| Tag | Content |
|---|
| CPLM ID | CPLM-006307 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein SGE1 |
Protein Synonyms/Alias | 10-N-nonyl acridine orange resistance protein; Crystal violet resistance protein |
Gene Name | SGE1 |
Gene Synonyms/Alias | NOR1; YPR198W; P9677.3 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 200 | WLPSKIKKIMNYDYG | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Drug export permease. Multi-copy suppressor of loss-of- function mutation of GAL11. Involved specifically in transcription of GAL4-dependent genes. Can link GAL4 with the basal transcription machinery if GAL11 is missing. Confers resistance to 10-N-nonyl acridine orange (NAO) and in general to cationic dyes. |
Sequence Annotation | |
Keyword | Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 543 AA |
Protein Sequence | MKSTLSLTLC VISLLLTLFL AALDIVIVVT LYDTIGIKFH DFGNIGWLVT GYALSNAVFM 60
LLWGRLAEIL GTKECLMISV IVFEIGSLIS ALSNSMATLI SGRVVAGFGG SGIESLAFVV 120
GTSIVRENHR GIMITALAIS YVIAEGVGPF IGGAFNEHLS WRWCFYINLP IGAFAFIILA 180
FCNTSGEPHQ KMWLPSKIKK IMNYDYGELL KASFWKNTFE VLVFKLDMVG IILSSAGFTL 240
LMLGLSFGGN NFPWNSGIII CFFTVGPILL LLFCAYDFHF LSLSGLHYDN KRIKPLLTWN 300
IASNCGIFTS SITGFLSCFA YELQSAYLVQ LYQLVFKKKP TLASIHLWEL SIPAMIATMA 360
IAYLNSKYGI IKPAIVFGVL CGIVGSGLFT LINGELSQSI GYSILPGIAF GSIFQATLLS 420
SQVQITSDDP DFQNKFIEVT AFNSFAKSLG FAFGGNMGAM IFTASLKNQM RSSQLNIPQF 480
TSVETLLAYS TEHYDGPQSS LSKFINTAIH DVFYCALGCY ALSFFFGIFT SSKKTTISAK 540
KQQ 543 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; IDA:SGD. GO:0015238; F:drug transmembrane transporter activity; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |