CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027384
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Seryl-tRNA synthetase, putative 
Protein Synonyms/Alias
  
Gene Name
 PF07_0073 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
176VDNKKKIKYYYHYDLacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 539 AA 
Protein Sequence
MVLDINLFRK EKGGNPDKIK ESERKRYHDE NNVDKVIEYD DKWRKCIFEL EELKKNINMI 60
NKEIGNKKKV DKNADVEDLK KKSLNIKEEI PKYQLKEKEL LKERNKYISK IGNLLNIKVV 120
CSDNEDNNKI VKTWGECKIL PACEENDNSI HDNVVNSNNI KRETLNNEVD NKKKIKYYYH 180
YDLLRKIGGA NFKKGIQVAG HRGYYLTGAG FLLHNAILQY ALNFLVNKKY IPVYPPFFMK 240
KNIMEECAEL DDFEETLYKI PSTSNSTLSS QQVSTSPTKI SSQADIKDDT TCNSQKKTNI 300
PSNEDLTRDD LFLIATSEQP LCALHKDETI ESKRLPLKYA GFSSCFRKEA GAHGKDIRGI 360
LRVHQFDKVE QFCIALPQHS NKIHEEMIQT CEEFYQSLNI PYRIVSIVSG ALNNAASIKY 420
DLEGFFPTSN QYRELVSCSN CTDYQSINLN IRYSDSSIKI NDLNKNTNLN DEMDSEYEHF 480
LTNFNTENKY HVHLLNGTMV AAQRFLCCLL ENYQNGEGIV VPEKLRPYMN NMDFIPFME 539 
Gene Ontology
 GO:0020011; C:apicoplast; ISS:GeneDB_Pfalciparum.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
 GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR002314; aa-tRNA-synt_IIb_cons-dom.
 IPR006195; aa-tRNA-synth_II.
 IPR002317; Ser-tRNA-ligase_type_1.
 IPR015866; Ser-tRNA-synth_1_N.
 IPR010978; tRNA-bd_arm. 
Pfam
 PF02403; Seryl_tRNA_N
 PF00587; tRNA-synt_2b 
SMART
  
PROSITE
 PS50862; AA_TRNA_LIGASE_II 
PRINTS
 PR00981; TRNASYNTHSER.