UniProt Accession

 NUCKS_RAT; Q9EPJ0 

Genbank Protein ID

 AJ237669; BC078818 

Genbank Nucleotide ID

 CAC20862.1; AAH78818.1 

Protein Name

 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 

Protein Synonyms/Alias

  

Gene Name

 Nucks1 

Gene Synonyms/Alias

 Nucks 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
9	SRPVRNRKVVDYSQF	acetylation	[1]
35	RDSGPPAKKIRSSPR	acetylation	[1]
52	KNKRRSGKNSQEDSE	acetylation	[1]
64	DSEDSEEKDVKTKKD	acetylation	[1]
67	DSEEKDVKTKKDDSH	acetylation	[1]
83	AEDSEDEKDDHKSVR	acetylation	[1]
87	EDEKDDHKSVRQQRQ	acetylation	[1]
98	QQRQAASKAASKQRE	acetylation	[1]
102	AASKAASKQREMLLE	acetylation	[1]
184	TVTPSPVKGKGKVGR	acetylation	[1]
186	TPSPVKGKGKVGRPT	acetylation	[1]
188	SPVKGKGKVGRPTAS	acetylation	[1]
201	ASKTSKEKTPSPKEE	acetylation	[1]
206	KEKTPSPKEEDEEAE	acetylation	[1]
218	EAESPPEKKTSASPP	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

 MOD_RES 14 14 Phosphoserine (By similarity).
 MOD_RES 19 19 Phosphoserine.
 MOD_RES 26 26 Phosphotyrosine (By similarity).
 MOD_RES 54 54 Phosphoserine (By similarity).
 MOD_RES 58 58 Phosphoserine (By similarity).
 MOD_RES 61 61 Phosphoserine (By similarity).
 MOD_RES 73 73 Phosphoserine (By similarity).
 MOD_RES 75 75 Phosphoserine (By similarity).
 MOD_RES 79 79 Phosphoserine (By similarity).
 MOD_RES 113 113 Phosphoserine (By similarity).
 MOD_RES 130 130 Phosphoserine (By similarity).
 MOD_RES 132 132 Phosphoserine (By similarity).
 MOD_RES 144 144 Phosphoserine (By similarity).
 MOD_RES 179 179 Phosphothreonine (By similarity).
 MOD_RES 181 181 Phosphoserine (By similarity).
 MOD_RES 202 202 Phosphothreonine (By similarity).
 MOD_RES 204 204 Phosphoserine (By similarity).
 MOD_RES 214 214 Phosphoserine.
 MOD_RES 223 223 Phosphoserine (By similarity).
 MOD_RES 229 229 Phosphoserine (By similarity).
 MOD_RES 234 234 Phosphoserine (By similarity).
 MOD_RES 240 240 Phosphoserine (By similarity).  

Keyword

 Complete proteome; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 243 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:RGD.
 GO:0005634; C:nucleus; IDA:RGD.
 GO:0003690; F:double-stranded DNA binding; TAS:RGD.
 GO:0003697; F:single-stranded DNA binding; TAS:RGD.
 GO:0051726; P:regulation of cell cycle; TAS:RGD. 

Interpro

 IPR026633; NUCKS1. 

Pfam

  

SMART

  

PROSITE

  

PRINTS