| Tag | Content |
|---|
| CPLM ID | CPLM-013138 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | UDP-glucuronosyltransferase 3A1 |
Protein Synonyms/Alias | UDPGT 3A1 |
Gene Name | Ugt3a1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 68 | GDIPDFRKENSSYQV | ubiquitination | [1] | | 86 | RLPEDQQKTFENRWH | ubiquitination | [1] | | 127 | CSHLLSRKDIMELLQ | ubiquitination | [1] | | 404 | NMVRVEAKNLGVSIQ | ubiquitination | [1] | | 441 | KTAAMASKVIRQSHP | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity). |
Sequence Annotation | CARBOHYD 70 70 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Glycoprotein; Glycosyltransferase; Membrane; Reference proteome; Signal; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 523 AA |
Protein Sequence | MAAHRSWLLV SFFLLEVLLL EAAKILTIST LSASHYILMN RVSQILQGGG HDVIKLLYEG 60
GDIPDFRKEN SSYQVINWRL PEDQQKTFEN RWHRLIDEYA YGRSKYHTLL KIHQYFADLC 120
SHLLSRKDIM ELLQKENFDL VLLDSMDLCS FLIVEKLGKR FVSFLPFQFS YMDFGLPNAP 180
LSYAPVYGSG LTDQMDFWGR VKNILMFFHF TKKRRDIFSQ YGNTVQEHFA EGSQPVLSDL 240
LLKAELWFVN SDFALDFARP LFPNTVYVGG LLDKPVQPIP QDLEDFISQF GDSGFVLVAL 300
GSVVSMIQSK EIIKEMNSAF AHLPQGVLWT CKSSHWPKDV SLAPNVKIMD WLPQIDLLAH 360
PSIRLFVTHG GMNSVMEAVH HGVPMVGIPF FGDQPENMVR VEAKNLGVSI QLQTLKAESF 420
LLTMKEVIED QRYKTAAMAS KVIRQSHPLT PAQRLVGWID HILQTGGAAH LKPYAFQQPW 480
HEQYMLDVFL FLLGLTLGTL WLSVKVLVAV TRYLSISRKV KQA 523 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0043541; C:UDP-N-acetylglucosamine transferase complex; ISO:MGI. GO:0015020; F:glucuronosyltransferase activity; ISO:MGI. GO:0071412; P:cellular response to genistein; ISO:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |