CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030856
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein O-mannosyl-transferase 1 
Protein Synonyms/Alias
 cDNA FLJ59530, highly similar to Protein O-mannosyl-transferase 1 (EC 2.4.1.109) 
Gene Name
 POMT1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
91TLRNVFGKPVPCWLHubiquitination[1]
126QVTCYPFKDVNNWWIubiquitination[1]
135VNNWWIVKDPRRHQLubiquitination[1, 2]
215GSDTDVWKTILSEVRubiquitination[1, 3]
253QLEIVGEKLSRGYHGubiquitination[1]
450SLSPHELKALRWKDSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 465 AA 
Protein Sequence
MAIFCGTELE QVCVFCHLLA RAVALLVIPV VLYLLFFYVH LILVFRSGPH DQIMSSAFQA 60
SLEGGLARIT QGQPLEVAFG SQVTLRNVFG KPVPCWLHSH QDTYPMIYEN GRGSSHQQQV 120
TCYPFKDVNN WWIVKDPRRH QLVVSSPPRP VRHGDMVQLV HGMTTRSLNT HDVAAPLSPH 180
SQEVSCYIDY NISMPAQNLW RLEIVNRGSD TDVWKTILSE VRFVHVNTSA VLKLSGAHLP 240
DWGYRQLEIV GEKLSRGYHG STVWNVEEHR YGASQEQRER ERELHSPAQV DVSRNLSFMA 300
RFSELQAQIH LLGNIVIWVS GSLALAIYAL LSLWYLLRRR RNVHDLPQDA WLRWVLAGAL 360
CAGGWAVNYL PFFLMEKTLF LYHYLPALTF QILLLPVVLQ HISDHLCRSQ LQRSIFSALV 420
VAWYSSACHV SNTLRPLTYG DKSLSPHELK ALRWKDSWDI LIRKH 465 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0000030; F:mannosyltransferase activity; IEA:InterPro.
 GO:0006493; P:protein O-linked glycosylation; IEA:InterPro. 
Interpro
 IPR027005; GlyclTrfase_39_like.
 IPR003342; Glyco_trans_39.
 IPR016093; MIR_motif. 
Pfam
 PF02815; MIR
 PF02366; PMT 
SMART
 SM00472; MIR 
PROSITE
 PS50919; MIR 
PRINTS