CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038291
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Gm20425 
Protein Synonyms/Alias
  
Gene Name
 Gm20425 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
134QLNQLEGKKSCHTGLubiquitination[1]
238LCLDNTRKPVDQYEDubiquitination[1]
264VARKNNGKEDLIWEIubiquitination[1]
283QEHFGKGKSKDFQLFacetylation[2]
285HFGKGKSKDFQLFSSubiquitination[1]
296LFSSPLGKDLLFKDSubiquitination[1]
301LGKDLLFKDSAFGLLacetylation[3]
301LGKDLLFKDSAFGLLubiquitination[1]
453SITWNNLKGKKSCHTubiquitination[1]
517LKCAPNNKEEYNGYTubiquitination[1]
540KGDVAFVKHQTVLDNubiquitination[1]
653PEGTTPEKYLGAEYMubiquitination[1]
898IAMAKSAKLIQQQLEubiquitination[1]
906LIQQQLEKELNTLRVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [3] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 978 AA 
Protein Sequence
MRLTVGALLA CAALGLCLAV PDKTVKWCAV SEHENTKCIS FRDHMKTVLP PDGPRLACVK 60
KTSYPDCIKA ISASEADAMT LDGGWVYDAG LTPNNLKPVA AEFYGSVEHP QTYYYAVAVV 120
KKGTDFQLNQ LEGKKSCHTG LGRSAGWVIP IGLLFCKLSE PRSPLEKDPV AFPKLCQLCP 180
GCGCSSTQPF FGYVGAFKCL KDGGGDVAFV KHTTIFEVLP EKADRDQYEL LCLDNTRKPV 240
DQYEDCYLAR IPSHAVVARK NNGKEDLIWE ILKVAQEHFG KGKSKDFQLF SSPLGKDLLF 300
KDSAFGLLRV PPRMDYRLYL GHNYVTAIRN QQEGVCPEGS IDNSPVKWCA LSHLERTKCD 360
EWSIISEGKI ECESAETTED CIEKIVNGEA DAMTLDGGHA YIAGQCGLVP VMAEYYESSN 420
CAIPSQQGIF PKGYYAVAVV KASDTSITWN NLKGKKSCHT GVDRTAGWNI PMGMLYNRIN 480
HCKFDEFFSQ GCAPGYEKNS TLCDLCIGPL KCAPNNKEEY NGYTGAFRCL VEKGDVAFVK 540
HQTVLDNTEG KNPAEWAKNL KQEDFELLCP DGTRKPVKDF ASCHLAQAPN HVVVSRKEKA 600
ARVKAVLTSQ ETLFGGSDCT GNFCLFKSTT KDLLFRDDTK CFVKLPEGTT PEKYLGAEYM 660
QSVGNMRKCS TSPEIPLRDY NSRDAPRPTT AWSLEPRNFG GPGRLHTSFM ASANTRRVGD 720
GAGGAFQPYL DSLRQELQQR DPTLLSVAVA LLAVLLTLVF WKFIWSRKSS QRAVLFVGLC 780
DSGKTLLFVR LLTGQYRDTQ TSITDSSAIY KVNNNRGNSL TLIDLPGHES LRFQLLDRFK 840
SSARAVVFVV DSAAFQREVK DVAEFLYQVL IDSMALKNSP SLLIACNKQD IAMAKSAKLI 900
QQQLEKELNT LRVTRSAAPS TLDSSSTAPA QLGKKGKEFE FSQLPLKVEF LECSAKGGRG 960
DTGSADIQDL EKWLAKIA 978 
Gene Ontology
 GO:0005576; C:extracellular region; IEA:InterPro.
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0008199; F:ferric iron binding; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0006879; P:cellular iron ion homeostasis; IEA:InterPro.
 GO:0006826; P:iron ion transport; IEA:InterPro.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR024156; Small_GTPase_ARF.
 IPR019009; SRP_receptor_beta_su.
 IPR001156; Transferrin_fam.
 IPR018195; Transferrin_Fe_BS. 
Pfam
 PF09439; SRPRB
 PF00405; Transferrin 
SMART
 SM00094; TR_FER 
PROSITE
 PS51417; ARF
 PS00205; TRANSFERRIN_LIKE_1
 PS00206; TRANSFERRIN_LIKE_2
 PS00207; TRANSFERRIN_LIKE_3
 PS51408; TRANSFERRIN_LIKE_4 
PRINTS
 PR00422; TRANSFERRIN.