| Tag | Content |
|---|
| CPLM ID | CPLM-018056 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | SH3 domain and tetratricopeptide repeat-containing protein 1 |
Protein Synonyms/Alias | |
Gene Name | SH3TC1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 447 | QETLQKVKNVLEQCK | ubiquitination | [1] | | 619 | RKQKNREKCAQVVPK | ubiquitination | [1] | | 874 | NMVAVALKRTGRTRQ | ubiquitination | [1] | | 1047 | LGTERAYKSALDYTK | ubiquitination | [1] | | 1054 | KSALDYTKRSLGIFI | ubiquitination | [1] | | 1129 | DGAWEREKAVSFYRD | ubiquitination | [1] | | 1296 | NFLLDREKSLFFYQK | ubiquitination | [1] | | 1303 | KSLFFYQKARTFATE | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | DOMAIN 305 368 SH3.
REPEAT 560 593 TPR 1.
REPEAT 601 634 TPR 2.
REPEAT 665 698 TPR 3.
REPEAT 786 819 TPR 4.
REPEAT 863 896 TPR 5.
REPEAT 946 979 TPR 6.
REPEAT 1027 1063 TPR 7.
REPEAT 1192 1225 TPR 8.
REPEAT 1277 1311 TPR 9.
MOD_RES 1248 1248 Phosphotyrosine. |
Keyword | Complete proteome; Phosphoprotein; Polymorphism; Reference proteome; Repeat; SH3 domain; TPR repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1336 AA |
Protein Sequence | MENLPAVTTE EPTPMGRGPV GPSGGGSTRD QVRTVVMRPS VSWEKAGPEE AKAPVRGDEA 60
PPARVAGPAA GTPPCQMGVY PTDLTLQLLA VRRKSRLRDP GLQQTLRGQL RLLENDSREM 120
ARVLGELSAR LLSIHSDQDR IVVTFKTFEE IWKFSTYHAL GFTHHCLANL LMDQAFWLLL 180
PSEEEETAIQ VHVDENALRL THESLLIQEG PFFVLCPDHH VRVMTGPRDA GNGPQALRQA 240
SGAPQGEAAP ETDSSPPSPS VSSEEVAVAA APEPLIPFHQ WALRIPQDPI DDAMGGPVMP 300
GNPLMAVGLA SALADFQGSG PEEMTFRGGD LIEILGAQVP SLPWCVGRHA ASGRVGFVRS 360
SLISMQGPVS ELESAIFLNE EEKSFFSEGC FSEEDARQLL RRMSGTDVCS VYSLDSVEEA 420
ETEQPQEKEI PPPCLSLEPQ ETLQKVKNVL EQCKTCPGCP QEPASWGLCA ASSDVSLQDP 480
EEPSFCLEAE DDWEDPEALS SLLLFLNAPG YKASFRGLYD VALPWLSSVF RSFSDEEELT 540
GRLAQARGAA KKAGLLMALA RLCFLLGRLC SRRLKLSQAR VYFEEALGAL EGSFGDLFLV 600
VAVYANLASI YRKQKNREKC AQVVPKAMAL LLGTPDHICS TEAEGELLQL ALRRAVGGQS 660
LQAEARACFL LARHHVHLKQ PEEALPFLER LLLLHRDSGA PEAAWLSDCY LLLADIYSRK 720
CLPHLVLSCV KVASLRTRGS LAGSLRSVNL VLQNAPQPHS LPAQTSHYLR QALASLTPGT 780
GQALRGPLYT SLAQLYSHHG CHGPAITFMT QAVEASAIAG VRAIVDHLVA LAWLHVLHGQ 840
SPVALDILQS VRDAVVASED QEGVIANMVA VALKRTGRTR QAAESYYRAL RVARDLGQQR 900
NQAVGLANFG ALCLHAGASR LAQHYLLEAV RLFSRLPLGE CGRDFTHVLL QLGHLCTRQG 960
PAQQGKGYYE WALLVAVEMG HVESQLRAVQ RLCHFYSAVM PSEAQCVIYH ELQLSLACKV 1020
ADKVLEGQLL ETISQLYLSL GTERAYKSAL DYTKRSLGIF IDLQKKEKEA HAWLQAGKIY 1080
YILRQSELVD LYIQVAQNVA LYTGDPNLGL ELFEAAGDIF FDGAWEREKA VSFYRDRALP 1140
LAVTTGNRKA ELRLCNKLVA LLATLEEPQE GLEFAHMALA LSITLGDRLN ERVAYHRLAA 1200
LQHRLGHGEL AEHFYLKALS LCNSPLEFDE ETLYYVKVYL VLGDIIFYDL KDPFDAAGYY 1260
QLALAAAVDL GNKKAQLKIY TRLATIYHNF LLDREKSLFF YQKARTFATE LNVRRVNLPP 1320
LPLCGWAPWL APSHPR 1336 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |