CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034904
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Rasal1 
Protein Synonyms/Alias
 RAS protein activator like 1 (GAP1 like) (Predicted) 
Gene Name
 Rasal1 
Gene Synonyms/Alias
 Rasal1_predicted; rCG_21923 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
348RSNSLASKSMEQFMKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTPase activation; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 801 AA 
Protein Sequence
MAKSGSLSIR VVEGRALPAK DVSGSSDPYC LVKVDDEVVA RTATIWRSLS PFWGEEYTVH 60
LPLDFHHLAF YVLDEDTVGH DDIIGKISLS KEAITADPRG IDSWINLSRV DPDEEVQGEV 120
CLAVKLLEDA RGRCLRCHVR QARDLAPRDI SGTSDPFARV FWGSRSLETS TIKKTRFPHW 180
DEVLELREAP GTTSPLRVEL WDWDMVGKND FLGMVEFTPQ TLQQKPPNGW FRLLPFPRAE 240
DSGGSLGALR LKVRLTEDRV LPSQYYQPLM ELLLESVQGP AEEDTTSPLA LLEELASGDC 300
RQDLATKLVK LFLGRGLAGP FLDYLTRREV ARTNDPNTLF RSNSLASKSM EQFMKLVGMR 360
YLHEVLRPVI SRVFEEKKYM ELDPSKMDLN RSRRISFKGT PTEEQVRETS LGLLTGYLGS 420
VVDAIVSSAG RCPLALRLAF KQLQQCVEKR FPGMEHQDVK YLATSGFLFL RFFAPAILTP 480
KLFDLRDHHA DPQTSRSLLL LAKAVQSIGN LGQQLGQGKE QWLAPLHPFL LQSISRVRDF 540
LDQLVDVDGD EEAGGSTCAL VQPSTIVREG FLLKRKEEPA SLATRFAFKK RYFRLSGRDL 600
SYSKTPEWQV HSSIPLSCIR AVERVDEGAF QLPHVMQVVT QDGTGASHTT YLQCKNVNDL 660
NQWLSALRKA SAPNPGKLAA CHPGAFRSGR WTCCLQAERS AVGCSRTHSA VTLGDWSDPL 720
DPDAEAQMVY RQLLLGRDQL RLKLLEDSSL DTAPDVDPGK DSSAVDGPCA EVLAQQREAT 780
TRLLQVLEDL EQAHEEFQKR G 801 
Gene Ontology
 GO:0005737; C:cytoplasm; IBA:RefGenome.
 GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018029; C2_membr_targeting.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR001936; RasGAP.
 IPR023152; RasGAP_CS.
 IPR008936; Rho_GTPase_activation_prot.
 IPR001562; Znf_Btk_motif. 
Pfam
 PF00779; BTK
 PF00168; C2
 PF00169; PH
 PF00616; RasGAP 
SMART
 SM00107; BTK
 SM00239; C2
 SM00233; PH
 SM00323; RasGAP 
PROSITE
 PS50004; C2
 PS50003; PH_DOMAIN
 PS00509; RAS_GTPASE_ACTIV_1
 PS50018; RAS_GTPASE_ACTIV_2
 PS51113; ZF_BTK 
PRINTS