CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032474
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein tyrosine phosphatase, receptor type, D 
Protein Synonyms/Alias
 Receptor-type tyrosine-protein phosphatase delta 
Gene Name
 Ptprd 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
904KSSLPNSKEVPSHHPubiquitination[1]
977HSNLEVNKPKNRYANubiquitination[1]
1245TGMELEFKRLASSKAubiquitination[1]
1266SANLPCNKFKNRLVNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Protein phosphatase; Receptor; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1508 AA 
Protein Sequence
MPLTNCRMVP VARPLSLLLT FFLCACAETP PRFTRTPVDQ TGVSGGVASF ICQATGDPRP 60
KIVWNKKGKK VSNQRFEVIE FDDGSGSVLR IQPLRTPRDE AIYECVASNN VGEISVSTRL 120
TVLREDQIPR GFPTIDMGPQ LKVVERTRTA TMLCAASGNP DPEITWFKDF LPVDTSNNNG 180
RIKQLRSESI GGTPIRGALQ IEQSEESDQG KYECVATNSA GTRYSAPANL YVRELREVRR 240
VPPRFSIPPT NHEIMPGGSV NITCVAVGSP MPYVKWMLGA EDLTPEDDMP IGRNVLELND 300
VRQSANYTCV AMSTLGVIEA IAQITVKALP KPPGTPVVTE STATSITLTW DSGNPEPVSY 360
YIIQHKPKNS EEPYKEIDGI ATTRYSVAGL SPYSDYEFRV VAVNNIGRGP ASEPVLTQTS 420
EQAPSSAPRD VQARMLSSTT ILVQWKEPEE PNGQIQGYRV YYTMDPTQHV NNWMKHNVAD 480
SQITTIGNLV PQKTYSVKVL AFTSIGDGPL SSDIQVITQT GVPGQPLNFK AEPESETSIL 540
LSWTPPRSDT IASYELVYRD GDQGEEQRIT IEPGTSYRLQ GLKPNSLYYF RLSARSPQGL 600
GASTAEISAR TMQSMFAKNF HVKAVMKTSV LLSWEIPENY NSAMPFKILY DDGKMVEEVD 660
GRATQKLIVN LKPEKSYSFV LTNRGNSAGG LQHRVTAKTA PDVLRTKPAF IGKTNLDGMI 720
TVQLPDVPAN ENIKGYYIII VPLKKSRGKF IKPWESPDEM ELDELLKEIS RKRRSIRYGR 780
EVELKPYIAA HFDVLPTEFT LGDDKHYGGF TNKQLQSGQE YVFFVLAVMD HAESKMYATS 840
PYSDPVVSMD LDPQPITDEE EGLIWVVGPV LAVVFIICIV IAILLYKRKR AESESRKSSL 900
PNSKEVPSHH PTDPVELRRL NFQTPGMASH PPIPILELAD HIERLKANDN LKFSQEYESI 960
DPGQQFTWEH SNLEVNKPKN RYANVIAYDH SRVLLSAIEG IPGSDYVNAN YIDGYRKQNA 1020
YIATQGSLPE TFGDFWRMIW EQRSATVVMM TKLEERSRVK CDQYWPSRGT ETHGLVQVTL 1080
LDTVELATYC VRTFALYKNG SSEKREVRQF QFTAWPDHGV PEHPTPFLAF LRRVKTCNPP 1140
DAGPMVVHCS AGVGRTGCFI VIDAMLERIK HEKTVDIYGH VTLMRAQRNY MVQTEDQYIF 1200
IHDALLEAVT CGNTEVPARN LYAYIQKLTQ IETGENVTGM ELEFKRLASS KAHTSRFISA 1260
NLPCNKFKNR LVNIMPYEST RVCLQPIRGV EGSDYINASF LDGYRQQKAY IATQGPLAET 1320
TEDFWRMLWE HNSTIVVMLT KLREMGREKC HQYWPAERSA RYQYFVVDPM AEYNMPQYIL 1380
REFKVTDARD GQSRTVRQFQ FTDWPEQGVP KSGEGFIDFI GQVHKTKEQF GQDGPISVHC 1440
SAGVGRTGVF ITLSIVLERM RYEGVVDIFQ TVKMLRTQRP AMVQTEDQYQ FCYRAALEYL 1500
GSFDHYAT 1508 
Gene Ontology
 GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
 GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. 
Interpro
 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003598; Ig_sub2.
 IPR000387; Tyr/Dual-sp_Pase.
 IPR016130; Tyr_Pase_AS.
 IPR000242; Tyr_Pase_rcpt/non-rcpt. 
Pfam
 PF00041; fn3
 PF07679; I-set
 PF00102; Y_phosphatase 
SMART
 SM00060; FN3
 SM00408; IGc2
 SM00194; PTPc 
PROSITE
 PS50853; FN3
 PS50835; IG_LIKE
 PS00383; TYR_PHOSPHATASE_1
 PS50056; TYR_PHOSPHATASE_2
 PS50055; TYR_PHOSPHATASE_PTP 
PRINTS
 PR00700; PRTYPHPHTASE.