UniProt Accession

 CRIPT_HUMAN; Q9P021 

Genbank Protein ID

 AF161488; AK291298; AC018682; CH471053; BC006980; BC018653 

Genbank Nucleotide ID

 AAF29103.1; BAF83987.1; AAY14836.1; EAX00239.1; AAH06980.1; AAH18653.1 

Protein Name

 Cysteine-rich PDZ-binding protein 

Protein Synonyms/Alias

 Cysteine-rich interactor of PDZ three; Cysteine-rich interactor of PDZ3 

Gene Name

 CRIPT 

Gene Synonyms/Alias

 HSPC139 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
20	VITPDTWKDGARNTT	ubiquitination	[1]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

 Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses (By similarity). 

Sequence Annotation

 REGION 95 101 Sufficient for interaction with DLG4.
 REGION 98 101 PDZ3-binding.  

Keyword

 Cell junction; Cell projection; Complete proteome; Cytoplasm; Reference proteome; Synapse. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 101 AA 

Protein Sequence

Gene Ontology

 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0043198; C:dendritic shaft; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0014069; C:postsynaptic density; IEA:Compara.
 GO:0031122; P:cytoplasmic microtubule organization; IEA:Compara.
 GO:0045184; P:establishment of protein localization; IEA:Compara. 

Interpro

 IPR019367; PDZ-binding_CRIPT. 

Pfam

 PF10235; Cript 

SMART

  

PROSITE

  

PRINTS