CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-012921
UniProt Accession
TSC3_YEAST
;
Q3E790
;
D6VQ58
Genbank Protein ID
Z35927
;
BK006936
Genbank Nucleotide ID
DAA07178.1
Protein Name
Serine palmitoyltransferase-regulating protein TSC3
Protein Synonyms/Alias
Temperature-sensitive CSG2-mutant suppressor protein 3
Gene Name
TSC3
Gene Synonyms/Alias
YBR058C-A
Created Date
July 27, 2013
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
NCBI Taxa ID
559292
Lysine Modification
Position
Peptide
Type
References
15
MVYIPTT
K
EAKRRNG
ubiquitination
[1]
Reference
[1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
Nat Methods. 2013 Jul;10(7):676-82. [
PMID: 23749301
]
Functional Description
Stimulates the activity of serine palmitoyltransferase (SPT).
Sequence Annotation
Keyword
Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
80 AA
Protein Sequence
MTQHKSSMVY IPTTKEAKRR NGKSEGILNT IEEVVEKLYW TYYIHLPFYL MASFDSFFLH 60
VFFLTIFSLS FFGILKYCFL 80
Gene Ontology
GO:0016021
; C:integral to membrane; IEA:UniProtKB-KW.
GO:0035339
; C:SPOTS complex; IDA:UniProtKB.
GO:0008047
; F:enzyme activator activity; IDA:SGD.
GO:0006666
; P:3-keto-sphinganine metabolic process; IPI:SGD.
GO:0030148
; P:sphingolipid biosynthetic process; TAS:SGD.
Interpro
Pfam
SMART
PROSITE
PRINTS