CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009284
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ras-related protein Rab-4B 
Protein Synonyms/Alias
  
Gene Name
 RAB4B 
Gene Synonyms/Alias
 PP1596 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
207CARTILNKIDSGELDubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Protein transport. Probably involved in vesicular traffic (By similarity). 
Sequence Annotation
 NP_BIND 15 23 GTP.
 NP_BIND 63 67 GTP (By similarity).
 NP_BIND 121 124 GTP.
 NP_BIND 151 153 GTP.
 MOTIF 37 45 Effector region (By similarity).
 MOD_RES 213 213 Cysteine methyl ester (By similarity).
 LIPID 211 211 S-geranylgeranyl cysteine (By
 LIPID 213 213 S-geranylgeranyl cysteine (By  
Keyword
 3D-structure; Alternative splicing; Cell membrane; Complete proteome; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Prenylation; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 213 AA 
Protein Sequence
MSVSLPLTVM VRERDWIGIH LFSLYLSLPV GIPDFGSIWS DFLFKFLVIG SAGTGKSCLL 60
HQFIENKFKQ DSNHTIGVEF GSRVVNVGGK TVKLQIWDTA GQERFRSVTR SYYRGAAGAL 120
LVYDITSRET YNSLAAWLTD ARTLASPNIV VILCGNKKDL DPEREVTFLE ASRFAQENEL 180
MFLETSALTG ENVEEAFLKC ARTILNKIDS GELDPERMGS GIQYGDASLR QLRQPRSAQA 240
VAPQPCGC 248 
Gene Ontology
 GO:0005622; C:intracellular; NAS:UniProtKB.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; NAS:UniProtKB.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003579; Small_GTPase_Rab_type. 
Pfam
 PF00071; Ras 
SMART
 SM00175; RAB 
PROSITE
 PS51419; RAB 
PRINTS
 PR00449; RASTRNSFRMNG.