UniProt Accession

 H0Y9E6_HUMAN; H0Y9E6 

Genbank Protein ID

 AC022107 

Genbank Nucleotide ID

  

Protein Name

 Centromere protein H 

Protein Synonyms/Alias

  

Gene Name

 CENPH 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
58	ALKKNLEKISRQSSV	ubiquitination	[1, 2]
71	SVLMDNMKHLLELNK	ubiquitination	[1, 2, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 187 AA 

Protein Sequence

Gene Ontology

 GO:0000777; C:condensed chromosome kinetochore; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0043515; F:kinetochore binding; IEA:InterPro.
 GO:0051301; P:cell division; IEA:InterPro.
 GO:0007059; P:chromosome segregation; IEA:InterPro. 

Interpro

 IPR008426; Centromere_CenpH. 

Pfam

 PF05837; CENP-H 

SMART

  

PROSITE

  

PRINTS