| Tag | Content |
|---|
| CPLM ID | CPLM-011743 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase |
Protein Synonyms/Alias | Asparagine-linked glycosylation protein 6; Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase; Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase |
Gene Name | ALG6 |
Gene Synonyms/Alias | YOR002W; UNA544 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 452 | ITPRFLPKSLTPGPS | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol. |
Sequence Annotation | |
Keyword | Complete proteome; Endoplasmic reticulum; Glycosyltransferase; Membrane; Reference proteome; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 544 AA |
Protein Sequence | MAIGKRLLVN KPAEESFYAS PMYDFLYPFR PVGNQWLPEY IIFVCAVILR CTIGLGPYSG 60
KGSPPLYGDF EAQRHWMEIT QHLPLSKWYW YDLQYWGLDY PPLTAFHSYL LGLIGSFFNP 120
SWFALEKSRG FESPDNGLKT YMRSTVIISD ILFYFPAVIY FTKWLGRYRN QSPIGQSIAA 180
SAILFQPSLM LIDHGHFQYN SVMLGLTAYA INNLLDEYYA MAAVCFVLSI CFKQMALYYA 240
PIFFAYLLSR SLLFPKFNIA RLTVIAFATL ATFAIIFAPL YFLGGGLKNI HQCIHRIFPF 300
ARGIFEDKVA NFWCVTNVFV KYKERFTIQQ LQLYSLIATV IGFLPAMIMT LLHPKKHLLP 360
YVLIACSMSF FLFSFQVHEK TILIPLLPIT LLYSSTDWNV LSLVSWINNV ALFTLWPLLK 420
KDGLHLQYAV SFLLSNWLIG NFSFITPRFL PKSLTPGPSI SSINSDYRRR SLLPYNVVWK 480
SFIIGTYIAM GFYHFLDQFV APPSKYPDLW VLLNCAVGFI CFSIFWLWSY YKIFTSGSKS 540
MKDL 544 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; IMP:SGD. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; ISM:SGD. GO:0042281; F:dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity; IMP:SGD. GO:0009060; P:aerobic respiration; IMP:SGD. GO:0006486; P:protein glycosylation; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |