CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-018618
UniProt Accession
SYUB_MOUSE
;
Q91ZZ3
Genbank Protein ID
AF348164
;
AF348162
;
AF348163
;
BC019409
Genbank Nucleotide ID
AAK83238.1
;
AAK83238.1
;
AAK83238.1
;
AAH19409.1
Protein Name
Beta-synuclein
Protein Synonyms/Alias
Gene Name
Sncb
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Mus musculus (Mouse)
NCBI Taxa ID
10090
Lysine Modification
Position
Peptide
Type
References
12
MKGLSMA
K
EGVVAAA
ubiquitination
[1]
57
GVASVAE
K
TKEQASH
ubiquitination
[1]
Reference
[1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [
PMID: 22790023
]
Functional Description
May be involved in neuronal plasticity (By similarity).
Sequence Annotation
REPEAT 20 30 1.
REPEAT 31 41 2.
REPEAT 42 55 3; approximate.
REPEAT 56 66 4.
REGION 20 66 4 X 11 AA tandem repeats of [EGS]-K-T-K-
MOD_RES 117 117 Phosphoserine; by BARK1, CK2 and GRK5 (By
Keyword
Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome; Repeat.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
133 AA
Protein Sequence
MDVFMKGLSM AKEGVVAAAE KTKQGVTEAA EKTKEGVLYV GSKTSGVVQG VASVAEKTKE 60
QASHLGGAVF SGAGNIAAAT GLVKKEEFPT DLKPEEVAQE AAEEPLIEPL MEPEGESYED 120
SPQEEYQEYE PEA 133
Gene Ontology
GO:0005794
; C:Golgi apparatus; IEA:Compara.
GO:0030426
; C:growth cone; IEA:Compara.
GO:0005739
; C:mitochondrion; IDA:MGI.
GO:0043025
; C:neuronal cell body; IEA:Compara.
GO:0005634
; C:nucleus; IEA:Compara.
GO:0045202
; C:synapse; IDA:MGI.
GO:0043195
; C:terminal bouton; IEA:Compara.
GO:0005509
; F:calcium ion binding; IEA:Compara.
GO:0042417
; P:dopamine metabolic process; IGI:MGI.
GO:0043524
; P:negative regulation of neuron apoptotic process; IGI:MGI.
GO:0050808
; P:synapse organization; IGI:MGI.
GO:0007268
; P:synaptic transmission; IGI:MGI.
Interpro
IPR001058
; Synuclein.
IPR002461
; Synuclein_beta.
Pfam
PF01387
; Synuclein
SMART
PROSITE
PRINTS
PR01213
; BSYNUCLEIN.
PR01211
; SYNUCLEIN.