CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013017
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Enoyl-CoA hydratase domain-containing protein 2, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Echdc2 
Gene Synonyms/Alias
 D4Ertd765e 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
101FCAGADLKEREQMSDacetylation[1]
292FREKRAPKFVGK***acetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Fatty acid metabolism; Lipid metabolism; Lyase; Mitochondrion; Reference proteome; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 296 AA 
Protein Sequence
MLRVLPRALR LPCSWRFSGA RDCASHATTR TPEIQVQALT GPNQGITEIL MNRPNARNAL 60
GNVFVSELLE ALAQLREDQQ VRVLLFRSAV KGVFCAGADL KEREQMSDVE VGTFVQRLRG 120
LMSEIAAFPV PTIAAMDGFA LGGGLELALA CDLRIAASSA VMGLIETTRG LLPGAGGTQR 180
LPRCLGVALA KELIFTGRRL NGAQARELGL VNHAVAQNEE GNAAYHRALA LAQEILPQAP 240
IAVRLGKVAI DRGMEVDIAS GMAIEQMCYA QNIPTQDRLE GMAAFREKRA PKFVGK 296 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
 GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW. 
Interpro
 IPR014748; Crontonase_C.
 IPR001753; Crotonase_core_superfam.
 IPR018376; Enoyl-CoA_hyd/isom_CS. 
Pfam
 PF00378; ECH 
SMART
  
PROSITE
 PS00166; ENOYL_COA_HYDRATASE 
PRINTS