UniProt Accession

 UBCD4_DROME; P52486; P91633 

Genbank Protein ID

 X92838; Y11349; AE014296; AY060381 

Genbank Nucleotide ID

 CAA63424.1; CAA72184.1; AAF50222.1; AAL25420.1 

Protein Name

 Ubiquitin-conjugating enzyme E2-22 kDa 

Protein Synonyms/Alias

 Ubiquitin carrier protein; Ubiquitin-protein ligase 

Gene Name

 UbcD4 

Gene Synonyms/Alias

 CG8284 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
14	SRIKREFKEVMRSEE	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Catalyzes the covalent attachment of ubiquitin to other proteins. 

Sequence Annotation

 DOMAIN 161 199 UBA.
 ACT_SITE 92 92 Glycyl thioester intermediate (By  

Keyword

 ATP-binding; Complete proteome; Ligase; Nucleotide-binding; Reference proteome; Ubl conjugation pathway. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 199 AA 

Protein Sequence

Gene Ontology

 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
 GO:0051726; P:regulation of cell cycle; IDA:FlyBase. 

Interpro

 IPR009060; UBA-like.
 IPR000449; UBA/transl_elong_EF1B_N.
 IPR015940; UBA/transl_elong_EF1B_N_euk.
 IPR000608; UBQ-conjugat_E2.
 IPR023313; UBQ-conjugating_AS.
 IPR016135; UBQ-conjugating_enzyme/RWD. 

Pfam

 PF00627; UBA
 PF00179; UQ_con 

SMART

 SM00165; UBA 

PROSITE

 PS50030; UBA
 PS00183; UBIQUITIN_CONJUGAT_1
 PS50127; UBIQUITIN_CONJUGAT_2 

PRINTS