CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000267
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Syntaxin-16 
Protein Synonyms/Alias
 Syn16 
Gene Name
 STX16 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
277KAEQYQKKNRKMLVIubiquitination[1]
280QYQKKNRKMLVILILubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
 SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. 
Sequence Annotation
 DOMAIN 230 292 t-SNARE coiled-coil homology.
 MOD_RES 35 35 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 325 AA 
Protein Sequence
MATRRLTDAF LLLRNNSIQN RQLLAEQLAD DRMALVSGIS LDPEAAIGVT KRPPPKWVDG 60
VDEIQYDVGR IKQKMKELAS LHDKHLNRPT LDDSSEEEHA IEITTQEITQ LFHRCQRAVQ 120
ALPSRARACS EQEGRLLGNV VASLAQALQE LSTSFRHAQS GYLKRMKNRE ERSQHFFDTS 180
VPLMDDGDDN TLYHRGFTED QLVLVEQNTL MVEEREREIR QIVQSISDLN EIFRDLGAMI 240
VEQGTVLDRI DYNVEQSCIK TEDGLKQLHK AEQYQKKNRK MLVILILFVI IIVLIVVLVG 300
VKSR 304 
Gene Ontology
 GO:0005794; C:Golgi apparatus; TAS:ProtInc.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005730; C:nucleolus; IDA:HPA.
 GO:0031201; C:SNARE complex; TAS:HGNC.
 GO:0005484; F:SNAP receptor activity; IDA:HGNC.
 GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:ProtInc.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0042147; P:retrograde transport, endosome to Golgi; IDA:UniProtKB. 
Interpro
 IPR006012; Syntaxin/epimorphin_CS.
 IPR006011; Syntaxin_N.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 
Pfam
 PF05739; SNARE
 PF00804; Syntaxin 
SMART
 SM00397; t_SNARE 
PROSITE
 PS00914; SYNTAXIN
 PS50192; T_SNARE 
PRINTS