CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010040
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 
Protein Synonyms/Alias
 BPG-independent PGAM; Phosphoglyceromutase; iPGM 
Gene Name
 gpmI 
Gene Synonyms/Alias
 pgm; MPN_628; MP214 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
240AVNGNVDKEQFALKDacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity). 
Sequence Annotation
 ACT_SITE 61 61 Phosphoserine intermediate (By
 METAL 11 11 Manganese 2 (By similarity).
 METAL 61 61 Manganese 2 (By similarity).
 METAL 397 397 Manganese 1 (By similarity).
 METAL 401 401 Manganese 1 (By similarity).
 METAL 438 438 Manganese 2 (By similarity).
 METAL 439 439 Manganese 2 (By similarity).
 METAL 456 456 Manganese 1 (By similarity).  
Keyword
 Complete proteome; Glycolysis; Isomerase; Manganese; Metal-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 508 AA 
Protein Sequence
MHKKVLLAIL DGYGISNKQH GNAVYHAKTP ALDSLIKDYP CVMLEASGEA VGLPQGQIGN 60
SEVGHLNIGA GRIVYTGLSL INQNIKTGAF HHNQVLLEAI ARAKANNAKL HLIGLFSHGG 120
VHSHMDHLYA LIKLAAPQVK MVLHLFGDGR DVAPCTMKSD LEAFMVFLKD YHNVIIGTLG 180
GRYYGMDRDQ RWDREEIAYN AILGNSKASF TDPVAYVQSA YDQKVTDEFL YPAVNGNVDK 240
EQFALKDHDS VIFFNFRPDR ARQMSHMLFQ TDYYDYTPKA GRKYNLFFVT MMNYEGIKPS 300
AVVFPPETIP NTFGEVIAHN KLKQLRIAET EKYAHVTFFF DGGVEVDLPN ETKCMVPSLK 360
VATYDLAPEM ACKGITDQLL NQINQFDLTV LNFANPDMVG HTGNYAACVQ GLEALDVQIQ 420
RIIDFCKANH ITLFLTADHG NAEEMIDSNN NPVTKHTVNK VPFVCTDTNI DLQQDSASLA 480
NIAPTILAYL GLKQPAEMTA NSLLISKK 508 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0046537; F:2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity; IEA:HAMAP.
 GO:0030145; F:manganese ion binding; IEA:HAMAP.
 GO:0006096; P:glycolysis; IEA:HAMAP. 
Interpro
 IPR017849; Alkaline_Pase-like_a/b/a.
 IPR017850; Alkaline_phosphatase_core.
 IPR011258; BPG-indep_PGM_N.
 IPR006124; Metalloenzyme.
 IPR005995; Pgm_bpd_ind. 
Pfam
 PF06415; iPGM_N
 PF01676; Metalloenzyme 
SMART
  
PROSITE
  
PRINTS