UniProt Accession

 A3KG36_MOUSE; A3KG36 

Genbank Protein ID

 AL807376; AL669976 

Genbank Nucleotide ID

 CAO77898.1; CAO77898.1 

Protein Name

 Glucose-6-phosphate 1-dehydrogenase 

Protein Synonyms/Alias

  

Gene Name

 G6pdx 

Gene Synonyms/Alias

 RP23-436K3.17-004 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
172	WNRIIVEKPFGRDLQ	acetylation	[1, 2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Carbohydrate metabolism; Complete proteome; Glucose metabolism; NADP; Oxidoreductase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 396 AA 

Protein Sequence

Gene Ontology

 GO:0004345; F:glucose-6-phosphate dehydrogenase activity; IDA:MGI.
 GO:0050661; F:NADP binding; IEA:InterPro.
 GO:0001998; P:angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure; IMP:MGI.
 GO:0048821; P:erythrocyte development; IMP:MGI.
 GO:0006749; P:glutathione metabolic process; IMP:MGI.
 GO:0032613; P:interleukin-10 production; IMP:MGI.
 GO:0032615; P:interleukin-12 production; IMP:MGI.
 GO:0006741; P:NADP biosynthetic process; IDA:MGI.
 GO:0019322; P:pentose biosynthetic process; IDA:MGI.
 GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
 GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.
 GO:0006979; P:response to oxidative stress; IMP:MGI.
 GO:0002033; P:vasodilation by angiotensin involved in regulation of systemic arterial blood pressure; IMP:MGI. 

Interpro

 IPR001282; G6P_DH.
 IPR019796; G6P_DH_AS.
 IPR022675; G6P_DH_C.
 IPR022674; G6P_DH_NAD-bd.
 IPR016040; NAD(P)-bd_dom. 

Pfam

 PF02781; G6PD_C
 PF00479; G6PD_N 

SMART

  

PROSITE

 PS00069; G6P_DEHYDROGENASE 

PRINTS

 PR00079; G6PDHDRGNASE.