| Tag | Content |
|---|
| CPLM ID | CPLM-017894 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | PRA1 family protein 3 |
Protein Synonyms/Alias | ADP-ribosylation factor-like protein 6-interacting protein 5; ARL-6-interacting protein 5; Aip-5; Addicsin; GTRAP3-18; Glutamate transporter EAAC1-interacting protein; Prenylated Rab acceptor protein 2; Protein JWa |
Gene Name | Arl6ip5 |
Gene Synonyms/Alias | Aip5; Jwa; Pra2; Praf3 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 31 | PDFRDISKWNNRVVS | ubiquitination | [1] | | 185 | KFADYISKARE**** | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic. |
Sequence Annotation | REGION 136 188 Targeting to endoplasmic reticulum
MOD_RES 1 1 N-acetylmethionine (By similarity). |
Keyword | Acetylation; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 188 AA |
Protein Sequence | MDVNLAPLRA WDDFFPGSDR FARPDFRDIS KWNNRVVSNL LYYQTNYLVV AAMMISVVGF 60
LSPFNMILGG VIVVLVFMGF VWAAHNKDIL RRMKKQYPTA FVMVVMLASY FLISMFGGVM 120
VFVFGITLPL LLMFIHASLR LRNLKNKLEN KMEGIGLKKT PMGIILDALE QQEDNINKFA 180
DYISKARE 188 |
Gene Ontology | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0015813; P:L-glutamate transport; IDA:MGI. GO:0051051; P:negative regulation of transport; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |