CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044770
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 WD repeat-containing protein 81 
Protein Synonyms/Alias
  
Gene Name
 Wdr81 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
341TECPTCQKELRGLVLubiquitination[1]
409FRLNKGDKQLDFTYEubiquitination[1]
960NANKYLLKPLIGAYEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1934 AA 
Protein Sequence
XAQGSRRRKV VLTAGSEGWS PSSGPDMEEL LRSVERDLNI DARQLALAPG GTHVVALVST 60
RWLASLRERR LGPCPRAEGL GEAEVRTLLQ RSVQRLPPGW TRVEVHGLRK RRLSYPLGGG 120
VPFEEGSCSP ETLTRFMQEV AAQNYRNLWR HAYHTYGQPY SHSTAPSALP ALDSIRQALQ 180
RVYGCTFLPV GESIPCLSNV RDGPCPSRGS PACPSLLRAE ALLESPEMLY VVHPYVQFSL 240
HDVVTFSPAK LTNSQAKVLF LLFRVLRAMD ACHRQGLACG ALSLHHIAVD EKLCSELRLD 300
LSAYEMPSED ENQEGSEEKN GTGIKSEKEG EGRTECPTCQ KELRGLVLDW VHGRISNFHY 360
LMQLNRLAGR RQGDPNYHPV LPWVVDFTTP YGRFRDLRKS KFRLNKGDKQ LDFTYEMTRQ 420
AFVAGGAGSG EPPHVPHHIS DVLSDITYYV YKARRTPRSV LCGHVRAQWE PHEYPATMER 480
MQTWTPDECI PEFYTDPSIF CSIHPDMPDL DVPAWCSSNQ EFVAAHRALL ESWEVSQDLH 540
HWIDLTFGYK LQGKEAVKEK NVCLHLVDAH THLTSYGVVQ LFDQPHPQRL AGSPALAPEP 600
PLIPRLLVQP IREATGQEDI SGQLINGAGR LVVEATPCET GWTRDRPGTG EDDLEQATEA 660
LDSISLPGKA GDQPGSSSSQ ASPGLLSFSA PSGSRPGRRS KAAGLDPGEG EEGKIVLPEG 720
FSPIQALEEL EKVGNFLAKG LGSQLEEPEK PHAQPPVHLQ SLFHRDMQVL GVLLAEMVFA 780
TRVRILQPDA PLWVRFEAVR GLCIRHSKDI PVSLQPVLDT LLQLSGPKSP MVSKKGKLDP 840
LFEYRPVSQG LPPPSPAQLL SPFSSVVPFP PYFPALHKFI LLYQARRVED EVQGRELAFA 900
LWQQLGAVLN DITPEGLEIL LPFVLSLMSE EHTAVYTAWY LFEPVAKALG PKNANKYLLK 960
PLIGAYESPC RLHGRFYLYT DCFVAQLVVR LGLQAFLTHL LPHVLQVLAG VEASQEEGKG 1020
LVGTTEDEES ELPVSGPGSC AFGEEIQMDG QPAASSGLGL PDYRSGVSFH DQADLPDTED 1080
FQAGLYVAES PQPQEAEAVS LGQLSDKSST SEASQGEERG GDDGGAPADK NSVKSGDSSQ 1140
DLKQSEGSEE EEEEEGCVVL EEDQEDEVTG TSELTLSDTM LSMETVVAPG DGRDREEEEE 1200
PLTEQTEGKE QKILLDTACK MVRWLSAKLG PTVASRHVAR NLLRLLTSCY VGPTRQQFTV 1260
SSDDTPPLNA GNIYQKRPVL GDIVSGPVLS CLLHIAYLYG EPVLTYQYLP YISYLVAPGS 1320
NSNPSRLNSR KEAGLLAAVT LTQKIIVYLS DTTLMDILPR ISHEVLLPVL GFLTSFVTGF 1380
PSGAQARTVL CVKTISLIAL ICLRIGQEMV QQHLSEPVAT FFQVFSHLHE LRQQDLPLDP 1440
KGCTEGQLPE ATFSDGQRRP VDPTLLEELQ KVFTLEMAYT IYVPFSCLLG DIIRKIIPNH 1500
ELVGELAGLY LESMSPSSRN PASMEPTMAS AGPEWDPQSG SCLQDDGHSG TFGSVLVGNR 1560
IQIPDSQPQS PGPLGSLSGV GSSGGLSNRN EDNALKRELP RSAHGLSGNW LAYWQYEIGV 1620
SQQDAHFHFH QIRLQSFPGH TGAVKCVAAL SSEDFFLSGS KDRTVRLWPL YNYGDGTNET 1680
ASRLIYAQHR KSVFYVGQLE APQYVVSCDG AVHVWDPFTG KTLRTVDPSD SRVPLTAVAV 1740
MPAPHTSITM ASSDSTLRFV DCRKPGLQHE FRLGGGLNPG LVRSLAVSPS GRSVVAGFSS 1800
GFMVLLDTRT GLVLRGWPAH EGDILQIKAV EGSVLISSSS DHSLTVWKEL EQKPTHHYKS 1860
ASDPIHTFDL YGSEVVTGTV ANKIGVCSLL EPPSQATTKL SSENFRGTLT SLALLPTKRH 1920
LLLGSDNGII RLLA 1934 
Gene Ontology
 GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro. 
Interpro
 IPR000409; BEACH_dom.
 IPR011009; Kinase-like_dom.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF02138; Beach
 PF00400; WD40 
SMART
 SM01026; Beach
 SM00320; WD40 
PROSITE
 PS50197; BEACH
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS