| Tag | Content |
|---|
| CPLM ID | CPLM-008213 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Tropomodulin-1 |
Protein Synonyms/Alias | Erythrocyte tropomodulin; E-Tmod |
Gene Name | Tmod1 |
Gene Synonyms/Alias | Tmod |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 91 | LVPYTGEKRGKVWVP | ubiquitination | [1] | | 228 | KENSYVKKFSIVGTR | ubiquitination | [1] | | 354 | LTGPIIPKCRSGV** | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity). |
Sequence Annotation | REGION 39 138 Tropomyosin-binding (Potential). |
Keyword | Actin-binding; Complete proteome; Cytoplasm; Cytoskeleton; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 359 AA |
Protein Sequence | MSYRRELEKY RDLDEDEILG ALTEEELRTL ENELDELDPD NALLPAGLRQ KDQTTKAPTG 60
PFKREELLDH LEKQAKEFKD REDLVPYTGE KRGKVWVPKQ KPMDPVLESV TLEPELEEAL 120
ANASDAELCD IAAILGMHTL MSNQQYYQAL GSSSIVNKEG LNSVIKPTQY KPVPDEEPNS 180
TDVEETLERI KNNDPELEEV NLNNIRNIPI PTLKAYAEAL KENSYVKKFS IVGTRSNDPV 240
AFALAEMLKV NKVLKTLNVE SNFISGAGIL RLVEALPHNT SLVELKIDNQ SQPLGNKVEM 300
EIVNMLEKNT TLLKFGYHFT QQGPRLRASN AMMSNNDLVR KRRLADLTGP IIPKCRSGV 359 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |