CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038736
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Laminin subunit beta-1 
Protein Synonyms/Alias
  
Gene Name
 Lamb1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1745LDGELDEKYKKVESLacetylation[1]
1784LLAQANSKLQLLEDLacetylation[1]
Reference
 [1] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Laminin EGF-like domain; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1834 AA 
Protein Sequence
MEGPLSSLPT FAFSPRYLSR KEDPKKRQAA CLLRPPSRAA SPRLRGLDMG LLQVFAFGVL 60
ALWGTRVCAQ EPEFSYGCAE GSCYPATGDL LIGRAQKLSV TSTCGLHKPE PYCIVSHLQE 120
DKKCFICDSR DPYHETLNPD SHLIENVVTT FAPNRLKIWW QSENGVENVT IQLDLEAEFH 180
FTHLIMTFKT FRPAAMLIER SSDFGKAWGV YRYFAYDCES SFPGISTGPM KKVDDIICDS 240
RYSDIEPSTE GEVIFRALDP AFKIEDPYSP RIQNLLKITN LRIKFVKLHT LGDNLLDSRM 300
EIREKYYYAV YDMVVRGNCF CYGHASECAP VDGVNEEVEG MVHGHCMCRH NTKGLNCELC 360
MDFYHDLPWR PAEGRNSNAC KKCNCNEHSS SCHFDMAVFL ATGNVSGGVC DNCQHNTMGR 420
NCEQCKPFYF QHPERDIRDP NLCEPCTCDP AGSENGGICD GYTDFSVGLI AGQCRCKLHV 480
EGERCDVCKE GFYDLSAEDP YGCKSCACNP LGTIPGGNPC DSETGYCYCK RLVTGQRCDQ 540
CLPQHWGLSN DLDGCRPCDC DLGGALNNSC SEDSGQCSCL PHMIGRQCNE VESGYYFTTL 600
DHYIYEAEEA NLGPGVIVVE RQYIQDRIPS WTGPGFVRVP EGAYLEFFID NIPYSMEYEI 660
LIRYEPQLPD HWEKAVITVQ RPGKIPASSR CGNTVPDDDN QVVSLSPGSR YVVLPRPVCF 720
EKGMNYTVRL ELPQYTASGS DVESPYTFID SLVLMPYCKS LDIFTVGGSG DGEVTNSAWE 780
TFQRYRCLEN SRSVVKTPMT DVCRNIIFSI SALIHQTGLA CECDPQGSLS SVCDPNGGQC 840
QCRPNVVGRT CNRCAPGTFG FGPNGCKPCD CHLQGSASAF CDAITGQCHC FQGIYARQCD 900
RCLPGYWGFP SCQPCQCNGH ALDCDTVTGE CLSCQDYTTG HNCERCLAGY YGDPIIGSGD 960
HCRPCPCPDG PDSGRQFARS CYQDPVTLQL ACVCDPGYIG SRCDDCASGF FGNPSDFGGS 1020
CQPCQCHHNI DTTDPEACDK ETGRCLKCLY HTEGDHCQLC QYGYYGDALR QDCRKCVCNY 1080
LGTVKEHCNG SDCHCDKATG QCSCLPNVIG QNCDRCAPNT WQLASGTGCG PCNCNAAHSF 1140
GPSCNEFTGQ CQCMPGFGGR TCSECQELFW GDPDVECRAC DCDPRGIETP QCDQSTGQCV 1200
CVEGVEGPRC DKCTRGYSGV FPDCTPCHQC FALWDAIIGE LTNRTHKFLE KAKALKISGV 1260
IGPYRETVDS VEKKVNEIKD ILAQSPAAEP LKNIGILFEE AEKLTKDVTE KMAQVEVKLT 1320
DTASQSNSTA GELGALQAEA ESLDKTVKEL AEQLEFIKNS DIQGALDSIT KYFQMSLEAE 1380
KRVNASTTDP NSTVEQSALT RDRVEDLMLE RESPFKEQQE EQARLLDELA GKLQSLDLSA 1440
VAQMTCGTPP GADCSESECG GPNCRTDEGE KKCGGPGCGG LVTVAHSAWQ KAMDFDRDVL 1500
SALAEVEQLS KMVSEAKVRA DEAKQNAQDV LLKTNATKEK VDKSNEDLRN LIKQIRNFLT 1560
EDSADLDSIE AVANEVLKME MPSTPQQLQN LTEDIRERVE TLSQVEVILQ QSAADIARAE 1620
LLLEEAKRAS KSATDVKVTA DMVKEALEEA EKAQVAAEKA IKQADEDIQG TQNLLTSIES 1680
ETAASEETLT NASQRISKLE RNVEELKRKA AQNSGEAEYI EKVVYSVKQN ADDVKKTLDG 1740
ELDEKYKKVE SLIAQKTEES ADARRKAELL QNEAKTLLAQ ANSKLQLLED LERKYEDNQK 1800
YLEDKAQELV RLEGEVRSLL KDISEKVAVY STCL 1834 
Gene Ontology
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0070062; C:extracellular vesicular exosome; IEA:Compara.
 GO:0005606; C:laminin-1 complex; IDA:MGI.
 GO:0043259; C:laminin-10 complex; IPI:MGI.
 GO:0005201; F:extracellular matrix structural constituent; IEA:Compara.
 GO:0043208; F:glycosphingolipid binding; IDA:MGI.
 GO:0005178; F:integrin binding; IMP:MGI.
 GO:0016477; P:cell migration; IMP:MGI.
 GO:0007566; P:embryo implantation; IMP:MGI.
 GO:0031175; P:neuron projection development; IDA:MGI.
 GO:0042476; P:odontogenesis; IEA:Compara.
 GO:0030335; P:positive regulation of cell migration; IEA:Compara.
 GO:0034446; P:substrate adhesion-dependent cell spreading; IEA:Compara. 
Interpro
 IPR002049; EGF_laminin.
 IPR013015; Laminin_IV.
 IPR008211; Laminin_N.
 IPR009053; Prefoldin. 
Pfam
 PF00053; Laminin_EGF
 PF00055; Laminin_N 
SMART
 SM00180; EGF_Lam
 SM00136; LamNT 
PROSITE
 PS01248; EGF_LAM_1
 PS50027; EGF_LAM_2
 PS51116; LAMININ_IVB
 PS51117; LAMININ_NTER 
PRINTS